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資料種別 図書

Hepatotoxicity : from genomics to in vitro and in vivo models / editor, Saura C. Sahu

詳細情報

タイトル Hepatotoxicity : from genomics to in vitro and in vivo models / editor, Saura C. Sahu
出版地(国名コード) GB
出版地Chichester, England
出版社John Wiley & Sons
出版年月日等 c2007
大きさ、容量等 xvi, 682 p. : ill. ; 26 cm
注記 ISBN : 9780470057162 (pbk. : alk. paper)
注記 Related URL: Publisher description http: //www.loc.gov/catdir/enhancements/fy0743/2007038233-d.html
注記 Related URL: Table of contents only http: //www.loc.gov/catdir/enhancements/fy0804/2007038233-t.html
注記 Related URL: Contributor biographical information http: //www.loc.gov/catdir/enhancements/fy0829/2007038233-b.html
注記 Includes bibliographical references and index
ISBN 9780470057162
LC番号 2007038233
OCLC番号 173182720
部分タイトル Current in vitro models to study drug-induced liver injury / Julio C. Davila ... [et al.] -- Utilization of an in vitro hepatotoxicity test in the early stage of drug discovery / Ikuo Horii ... [et al.] -- Use of hepatocytes for characterizing a candidate drug's metabolism and drug interaction potential / Srikanth C. Nallani, John M. Strong, and Shiew Mei Huang -- Human-based in vitro experimental systems for the evaluation of human drug safety / Albert P. Li -- Hepatocytes as a model for screening food-related hepatotoxins and studying mechanisms of their toxicity / Saura C. Sahu -- Some experimental models of liver damage / Pablo Muriel -- Application of short- and long-term hepatocyte cultures to predict toxicities / Gregor Tuschl ... [et al.] -- Biomarkers of mycotoxin exposure in liver toxicity / Angela J. Harris -- Mechanisms of toxic liver injury / Nora Anderson and Jurgen Borlak -- A role of cytochrome P450 in quinone-induced hepatotoxicity / Yasuhiro Ishihara and Norio Shimamoto -- A mechanistic view of troglitazone hepatotoxicity / Rawiwan Maniratanachote and Tsuyoshi Yokoi -- Role of the Kupffer cell in hepatotoxicity and hepatocarcinogenesis / James E. Klaunig ... [et al.] -- Sinusoidal cells in liver injury and repair / Carol C. Gardner and Debra L. Laskin -- Cytokines in liver diseases / Pablo Muriel -- Bile acids as modulators of apoptosis / Rui E. Castro ... [et al.] --
部分タイトル Drug-induced intrahepatic cholestasis by interaction with the hepatic bile salt export pump (BSEP) / Christoph Funk ... [et al.] -- Application of toxicogenomics in predicting hepatotoxicity: potentials and challenges / Wen Lin ... [et al.] -- Genomic profiling of liver injury / Kevin Gerrish and David E. Malarkey -- Use of DNA arrays in understanding hepatic test systems / Angela J. Harris and Daniel A. Casciano -- Prediction of hepatotoxicity based on the toxicogenomics database / Tetsuro Urushidani -- Relationship between N-acetyltransferase-2 gene polymorphism and isoniazid-induced hepatotoxicity / Yasuo Shimazu, Kunio Dobashi, and Masatomo Mori -- Human and animal-based differences in hepatic xenobiotic metabolism and toxicity / Peter J. O'Brien, Katie Chan, and Raymond J. Poon -- Hepatotoxicity in oncology drug development / Wei Chen, Kenneth Hastings, and John K. Leighton -- The potent rat hepatocarcinogen methapyrilene: an hypothesis regarding its hepatotoxicology / Daniel A. Casciano -- Botanical supplements and hepatotoxicity / Shabana Khan, Ikhlas Khan, and Larry Walker -- Physiologically based pharmokinetic modeling and risk assessment of hepatotoxicants / Kannan Krishnan
出版年(W3CDTF) 2007
件名(キーワード) Hepatotoksikoloji
件名(キーワード) Hepatotoxicology
件名(キーワード) Hépatotoxicité
件名(キーワード) Drug-Induced Liver Injury -- etiology
件名(キーワード) Drug Evaluation, Preclinical
件名(キーワード) Liver -- drug effects
件名(キーワード) Models, Biological
件名(キーワード) Toxicogenetics -- methods
NDLC SD74
NDLC SC344
LCC RC848.H48
DDC 616.3/623071
資料の種別 図書
言語(ISO639-2形式) eng : English

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