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Bioorganic & medicinal chemistry letters

Bioorganic & medicinal chemistry letters
紙記録メディア雑誌
Elsevier Science<Z54-J575>
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Direct evaluation of polarity of the ligand binding pocket in retinoid X receptor using a fluorescent solvatochromic agonist

Direct evaluation of polarity of the ligand binding pocket in retinoid X receptor using a fluorescent solvatochromic agonist
紙記事
Miura, Kizuku, Fujihara, Michiko, Watanabe, Masaki, Takamura, Yuta, Kawasaki, Mayu, Nakano, Shogo, Kakuta, HirokiElsevier BV2023-11-15Bioorganic & Medicinal Chemistry Letters96p.129536-
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Design, synthesis, structure–activity relationship studies, and evaluation of novel GLS1 inhibitors

Design, synthesis, structure–activity relationship studies, and evaluation of novel GLS1 inhibitors
デジタル記事
2023-05Bioorganic & Medicinal Chemistry Letters87p.129266-
全国の図書館
  • 掲載誌（ISSN）0960894X

11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent

11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent
デジタル記事
2023-04Bioorganic & Medicinal Chemistry Letters85p.129212-
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  • 掲載誌（ISSN）0960894X

Synthesis and biological evaluation of coumarin derivatives as selective CYP2A6 inhibitors

Synthesis and biological evaluation of coumarin derivatives as selective CYP2A6 inhibitors
デジタル記事
2023-04Bioorganic & Medicinal Chemistry Letters86p.129206-
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  • 掲載誌（ISSN）0960894X

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies
デジタル記事
2023-03Bioorganic & Medicinal Chemistry Letters83p.129168-
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  • 掲載誌（ISSN）0960894X

Design and synthesis of novel orexin 2 receptor agonists with a 1,3,5‑trioxazatriquinane skeleton

Design and synthesis of novel orexin 2 receptor agonists with a 1,3,5‑trioxazatriquinane skeleton
デジタル記事
2023-02Bioorganic & Medicinal Chemistry Letters82p.129151-
インターネットで読める全国の図書館
  • 掲載誌（ISSN）0960894X

Synthesis and biological evaluation of novel SN38-glucose conjugate for colorectal cancer treatment

Synthesis and biological evaluation of novel SN38-glucose conjugate for colorectal cancer treatment
デジタル記事
2023-02Bioorganic & Medicinal Chemistry Letters81p.129128-
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  • 掲載誌（ISSN）0960894X

A small molecule binding to TGGAA pentanucleotide repeats that cause spinocerebellar ataxia type 31

A small molecule binding to TGGAA pentanucleotide repeats that cause spinocerebellar ataxia type 31
デジタル記事
2023-01Bioorganic & Medicinal Chemistry Letters79p.129082-
全国の図書館
  • 掲載誌（ISSN）0960894X

Accumulation of lankamycin derivative with a branched-chain sugar from a blocked mutant of chalcose biosynthesis in Streptomyces rochei 7434AN4

Accumulation of lankamycin derivative with a branched-chain sugar from a blocked mutant of chalcose biosynthesis in Streptomyces rochei 7434AN4
デジタル記事
2023-01Bioorganic & Medicinal Chemistry Letters80p.129125-
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Synthesis of raloxifene-like quinoxaline derivatives by intramolecular electrophilic cyclization with disulfides

Synthesis of raloxifene-like quinoxaline derivatives by intramolecular electrophilic cyclization with disulfides
紙記事
Umezu, Yuhi, Horiyama, Eito, Nakai, Yuto, Ninomiya, Masayuki, Nishina, Atsuyoshi, Koketsu, MamoruElseviser2023Bioorganic & Medicinal Chemistry Letters26p.129415-
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  • 掲載誌（ISSN）0960894X

The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action

The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action
デジタル記事
2023-01Bioorganic & Medicinal Chemistry Letters80p.129110-
全国の図書館
  • 掲載誌（ISSN）0960894X

Fullerene derivatives as inhibitors of the SARS-CoV-2 main protease

Fullerene derivatives as inhibitors of the SARS-CoV-2 main protease
デジタル記事
2023-01Bioorganic & Medicinal Chemistry Letters80p.129121-
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Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity

Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity
デジタル記事
2022-12Bioorganic & Medicinal Chemistry Letters77p.129035-
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  • 掲載誌（ISSN）0960894X

Design, synthesis and activity evaluation of Hedgehog inhibitor Itraconazole derivatives in A549 cells

Design, synthesis and activity evaluation of Hedgehog inhibitor Itraconazole derivatives in A549 cells
デジタル記事
2022-11Bioorganic & Medicinal Chemistry Letters76p.129011-
全国の図書館
  • 掲載誌（ISSN）0960894X

Biocatalytic synthesis and evaluation of antioxidant and antibacterial activities of hydroxyequols

Biocatalytic synthesis and evaluation of antioxidant and antibacterial activities of hydroxyequols
デジタル記事
2022-10Bioorganic & Medicinal Chemistry Letters73p.128908-
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A 2′-modified uridine analog, 2′-O-(methylthiomethoxy)methyl uridine, for siRNA applications

A 2′-modified uridine analog, 2′-O-(methylthiomethoxy)methyl uridine, for siRNA applications
デジタル記事
2022-10Bioorganic & Medicinal Chemistry Letters74p.128939-
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Split luciferase-based estimation of cytosolic cargo concentration delivered intracellularly via attenuated cationic amphiphilic lytic peptides

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デジタル記事
Okano, Syusuke, 川口, 祥正, 河野, 健一, 廣瀨, 久昭, 今西, 未来, 二木, 史朗Elsevier BV2022-09-15Bioorganic & Medicinal Chemistry Letters72
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Split luciferase-based estimation of cytosolic cargo concentration delivered intracellularly via attenuated cationic amphiphilic lytic peptides

Split luciferase-based estimation of cytosolic cargo concentration delivered intracellularly via attenuated cationic amphiphilic lytic peptides
デジタル記事
2022-09-15Bioorganic & Medicinal Chemistry Letters72p.128875-
全国の図書館
  • 掲載誌（ISSN）0960894X

Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor

Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor
デジタル記事
2022-09Bioorganic & Medicinal Chemistry Letters72p.128869-
全国の図書館
  • 掲載誌（ISSN）0960894X