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- 要約等After axotomy, application of muscimol, a GABAA receptor agonist, induced an increase in intracellular Ca2+ ([Ca2+]i) in dorsal motor neurons of the vagus (DMV......ns). Elevation of [Ca2+]i by mus......ked by bicuculline, tetrodotoxin, and Ni2+. In axotomized DMV......d with gramicidin perforated-patch recordings, reversal potentials of the GABAA receptor-mediated response, pres......rium potential of Cl-, were more......ized than that in intact neurons. Thus, GABAA receptor-mediated excitation is suggested t......Cl- efflux out of the cell because of increased intracellular Cl-......ation ([Cl-]i) in axotomized neurons. Regulatio...
- 件名axotomy GABA excitation motoneuron NKCC1 Cl- Ca2+
デジタル記事
インターネットで読める全国の図書館
- 件名axotomy GABA excitation motoneuron NKCC1 Cl- Ca2+
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