検索結果 4 件

デジタル記事
Katsuya Hirano, Mayumi Hirano<Z53-D199>Journal of pharmacological sciences114(2) 2010.10p.127~133
インターネットで読める国立国会図書館全国の図書館
  • 要約等Cerebral vasospasm is a persisten......arterial narrowing typically observed during the 3 – 14 days after subarachnoid hemorrhage (SAH). Vasospasm is frequently ......n death, resulting in a poor prognos...... SAH. However, the mechanism underlying cerebral vasospasm remains elusive, and no effective therapeutic strate......A large amount of thrombin is produced during SAH. Recent investigations have uncovered a key role of the thrombin receptor in the pathogenesis of cerebral vasospasm. Thrombin has little contractile effect in the normal cerebral artery, but it induces an enhanced and prolonged contraction after SAH, owi...
  • 件名desensitization proteinase-activated receptor up-regulation subarachnoid hemorrhage vasoconstriction
  • 参照Combined argatroban a......gents prevents increased vascular contractility to thrombin and other ligands after subarachnoid haemorrhage The Unique Property of the Pulmonary Artery Regarding the Smooth Muscle Effects of Proteinase-Activated Receptor 1: The Possible Contribution to the Pathogenesis of Pulmonary Hypertension 『新しい肺高血圧治療戦略の提案』 プロテイナーゼ活性化型受...
デジタル記事
平野, 勝也日本薬理学会2010-10Journal of Pharmacological Sciences114p.127-133
インターネットで読める全国の図書館
デジタル記事
Hirano Katsuya, Hirano Mayumi2010Journal of Pharmacological Sciences114 2p.127-133
インターネットで読める全国の図書館
  • 要約等Cerebral vasospasm is a persisten......arterial narrowing typically observed during the 3 – 14 days after subarachnoid hemorrhage (SAH). Vasospasm is frequently ......n death, resulting in a poor prognos...... SAH. However, the mechanism underlying cerebral vasospasm remains elusive, and no effective therapeutic strate......A large amount of thrombin is produced during SAH. Recent investigations have uncovered a key role of the thrombin receptor in the pathogenesis of cerebral vasospasm. Thrombin has little contractile effect in the normal cerebral artery, but it induces an enhanced and prolonged contraction after SAH, owi...
  • 件名vasoconstriction subarachnoid hemorrhage up-regulation proteinase-activated receptor desensitization

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