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- 要約等...osis, which is the homeostatic phagocytosis of apoptotic cells, prevents the release of toxic intracel......ge. Impairment of efferocytosis ......as reported in alveolar macrophages (AMs) of patients with ......disease caused by smoking. In COPD, histone deacetylase (H......nvestigated whether the reduction of HDAC activity ......ssociated with the impairment of efferocytosis.......were collected by bronchoalveolar lavage and their ability to efferocytose apoptotic human polymorp...... Pre-treatment of AMs with cigarette smoke extract (CSE) ...... TSA inhibited the activity of Rac, a key mediator of efferocytosis. These TSA-indu...
- 参照...d upregulation of PD-L1 in airway epithelial cells via a STAT3-dependent mechanism
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