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デジタル電子書籍・電子雑誌図書
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- 件名cytokine immunological memory malaria Tfh Th1
- 一般注記...月日:令和3年12月1日 Author: Mbaya Ntita, Shin-Ichi Inoue, Jiun-Yu Ji...... Eriko Nozaki, Takuya Sakurai, ......, William R Heath, Katsuyuki Yui Citation: International Immunolog......gasaki University (長崎大学), 博士(医学) (2021-12-01)
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- 目次・記事ISYK1384_Ntita.pdf Suppl_figures.pdf
- 件名cytokine immunological memory malaria Tfh Th1
- 一般注記...月日:令和3年12月1日 Author: Mbaya Ntita, Shin-Ichi Inoue, Jiun-Yu Ji...... Eriko Nozaki, Takuya Sakurai, ......, William R Heath, Katsuyuki Yui Citation: International Immunolog......gasaki University (長崎大学), 博士(医学) (2021-12-01)
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- 目次・記事ishiyaku1384ronbun.pdf ishiyaku1384sinsa.pdf
- 並列タイトル等（連結）I 型インターフェロン産生はマラリア原虫 Plasmodium berghei ANKA と P. chabaudi 感染マウスの CD4+ T 細胞応答の違いを誘導する
- 並列タイトル等I 型インターフェロン産生はマラリア原虫 Plasmodium berghei ANKA と P. chabaudi 感染マウスの CD4+ T 細胞応答の違いを誘導する
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- 要約等<jats:p>Most people infected by EBV acqui......specific immunity, which then controls latent infection throughout their life. Immu......illance of EBV-infected cells by cytotoxic CD4+ T cells has been reco......ized; however, the molecular me......anism of generating cytotoxic effector T cells of the CD4+ subset remains poorly understood. Here we compared phenotypic features and the transcriptome of EBV-specific effector-memory CD4+ T cells and CD8+ T cells in mice and found that both T cell types show cytotoxicity and, to our surprise,......e expression patterns relating to cytotoxicity. Similar to cytotoxic CD8+ T cells, EBV-...
- 参照Discerning regulation of cis- and trans-presentation of CD8+ T-cell epitopes by EBV-enc......oncogene LMP-1 through self-aggregation Epstein–Barr virus: more than 50 years old and still providing surprises The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation CMV Status Drives Distinct Trajectories of CD4+ T Cell Differentiation Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer Epstein-Barr Virus BKRF4 Gene Product Is Required for Efficient Progeny Production Death by a Thousand Cuts: Granzyme Pathways of Progra...
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- 件名Molecular Biology Molecular Medicine
- 参照DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus Multi-dimensional analysis identified rheumatoid arthritis-driving pathway in human T cell
- 著者標目Laura A. Vella Ramin S. Herati E. John Wherry
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- DOI10.1371/journal.ppat.1007053
- 件名Virology Genetics Molecular Biology Immunology Microbiology Parasitology
- 参照Inhibition of T cell activation and function by the adaptor protein CIN85
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- 要約等<jats:title>Abstract</jats:title><jats:p>Abstract</jats:p><jats:p>Plasmodium parasites that infect humans are hig......lymorphic, and induce various infections ranging from an asymptomatic state to life-threatening diseases. However, how the differences between the parasites affect host immune responses during blood-stage infection remains largely unknown. We investigated the CD4+ T-cell immune responses in mice infected with P. berghei AN......udi AS (Pcc) using PbT-II cells, which recogn......ze a common epitope of these parasites. In the acute phase of infection, CD4+ T-cell responses in PbA-infected mice showed a lower inv...
- 件名Immunology General Medicine Immunology and Allergy
- 参照Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria Role of IL-10 in inhibiting protective immune responses against infection with heterologous Plasmodium parasites Immunological processes in malaria pathogenesis Cyclic GMP–AMP Synthase Is the Cytosolic Sensor o......omic DNA and Activates Type I IFN in Malaria CD49d marks Th1 and Tfh-like antigen-specific CD4+ T cells during <i>Plasmodium chabaudi</i> infection Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity <i>Plasmodiu...
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- 参照CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function
- 著者標目Deborah M. Brown Anna T. Lampe Aspen M. Workman
- 出版者（掲載誌）Frontiers Media SA
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- 参照The Role of CD4+ Resident Memory T Cells in Local Immunity in the Mucosal Tissue – Protection Versus Pathology – Divergence of Tissue-Memory T Cells: Distribution and Function-Based Classification Niches for the Long-Term Maintenance of Tissue-Resident Memory T Cells
- 著者標目...M. Pham L. Puddington K.M. Khanna L. Lefrançois B...
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- 参照Host responses to intestinal nematodes Role of eosinophils in protective immunity against secondary nematode infections
- 著者標目Tiffany Bouchery Ryan Kyle Fran...
- 出版者（掲載誌）Frontiers Media SA
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- 要約等<jats:title>Abstract</jats:title><jats:p>Acute HIV infection is characterized by massive loss of CD4 T cells from the gastrointestinal (GI) tract. Th17 cells are critical in the defense against microbes, particularly at mucosal surfac......re we analyzed Th17 cells in the blood, GI tract, and broncheoa...... lavage of HIV-infected and uninfected humans, and SIV-infected and uninfected sooty mangabeys. We found that (1) human Th17 cells are specific for extracellular bacterial and fungal antigens, but not common viral antigens; (2) Th17 cells are infected by HIV in vivo, but not preferentially so; (3) CD4 T cells in blood of HIV-infecte...
- 件名Cell Biology Hematology Immunology Biochemistry
- 参照CCR6 Functions as a New Coreceptor for Limited Primary Huma......y Viruses Impact of HIV Infection and Anti-Retroviral Therapy on the Immune Profi...... and Microbial Translocation in HIV-Infected Children in Vietnam Imbalanced Production of Cytokines by T Cells Associates with the Activation/Exhaustion Status of Memory T Cells in Chronic HIV Type 1 Infection Simian Immu......ficiency Virus Targeting of CXCR3 ......p> T Cells in Secondary Lymp......gans Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets
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- 件名Multidisciplinary
- 参照Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories Interleukin-27 promotes autophagy in human serum-induced primary m......phages via an mTOR- and LC3-independent pathway
- 寄与者Peter Sommer
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- 要約等<jats:title>Summary</jats:title><jats:p>Influenza A virus...... pandemics and the investigation of memory T helper (Th) cells that help maintain serological memory following infection is important for vaccine design. In this study we investigated <jats:italic>CD94</jats:italic> and <jats:italic>NKG2</jats:italic> gene expression in memory CD4 T‐cell clones established from the spleens of C57BL/10 (H‐2<jats:sup>b</jats:sup>) and BALB/c (H‐2<jats:sup>d</jats:sup>) mice infected with influenza A virus......d NKG2A/C/E proteins form heterodimeric membrane receptors that are involved in virus recognition. CD94 and NKG2 expression ...
- 参照CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function
- 著者標目Christine M. Graham Jillian R. Christensen D. Brian Thomas
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- 件名Hepatology
- 参照Apolipoprotein A-II Suppressed Concanavalin A-Induced Hepatitis via the Inhibition of CD4 T Cell Function Spred2 controls the severity of Concanavalin A-induced liver damage by limiting interferon-gamma production by CD4+ and CD8+ T cells Restoration of natural killer cell activity by interferon‐free direct‐acting antiviral combination therapy in chronic hepatitis C patients Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of......ibrosis Ribavirin downmodulates inducible costimulator on CD4<sup>+</sup> T cells and their interleukin‐10 secretion to assist in hep...
- 出版者（掲載誌）Ovid Technologies (Wolters Kluwer Health)