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- 参照... survival upon intraperitoneal crocidolite injection in female mice
- 参照8-oxoguanine causes spontan......s de novo germline mutations in mice. Oxidativ...... Damage to RNA and Expression Patterns of MTH1 in the Hippocampi of Senescence-Acc......ted SAMP8 Mice and Alzheimer’s Di......de pool sanitizing enzyme: Frien......c LSD1/KDM1A Isoform Regulates N......DNA Precursors in Huntington's Disease–...... Proliferation and Differentiation of Neural Stem/Pr......nitors migrate into the subcortical forebrain of postnatal mice...... LSD1 is a flavin‐dependent oxidative process 8-Oxoguanine causes neurodegeneration during MUTYH-mediate......rives Estrogen-Induced Gene Expr......ive DNA Damage and Delays Photoreceptor Cell Dea...
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- 件名8-oxoguanine adult neurogenesis major island of Calleja spontaneous lo......mpairment dopamine receptor D3
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- 要約等In mammals, including humans, MTH1 ...... 8-oxo-dGTPase and OGG1 with 8-oxoguanine DNA glycosylase minimize 8-oxoguanine accumulation in genomic DNA. We investigated age-......ed alterations in behavior, 8-oxoguanine levels, and neurogenesis in the brains of Mth1/Ogg1-doub......Ogg1-knockout, and human MTH1-tra......ntly decreased in wild-type mice with age, and females consistently ......tly suppressed in female but not male TO-DKO mice and markedly enhanced in female hMTH1-Tg mice.......l was impaired in middle-aged female TO-DKO mice. 8-Oxoguanine accumulation significantly increased in nuclear DNA, particularly in the dentate gyrus (DG), subve...
- 件名8-oxoguanine adult neurogenesis major island of Calleja spontaneous lo......mpairment dopamine receptor D3
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