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- 要約等...ular Mechanism and Treatment Stra......ovides answers and guidance on a ......ences in terms of fractures, fra......ty, disability and diminished quality of life. Written ......experts around the world, this bo......opulations. As the global populat......enia remains a therapeutic challenge and major public h......enotype remain and have hindered treatment
- 内容細目...ular Mechanism and Treatment Stra......tochondrial dysfunction to sarcopenia ......ion Sarcopenia and mitochondrial function Potential sources of mitochondrial dysfunction in aging React......ial DNA damage and aging Altered ......ng Association of reduced activity and mitochondrial dysfunction in sarcopenia ...... dysregulation of mitochondria i......is, mitophagy, and UPS can be mod......nces Chapter 2 The role of the neuromuscular ......al adaptations of the NMJ Age-related functional adaptations of the NMJ Preventing and managing the effects of aging on the NMJ Role of NMJ in sarcope...... a determinant of protein quality Dietary prote...
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- 要約等... insights into the operating principles of plants by highlighting the relationship between structure and function. It describes the quantitative determination of structural and mechanical par......eters, such as the material properties of a tissue, in c......tures, such as the ability of the tissue to cond......water or withstand bending forces......hers to understand the developmental ......nt organs over their life span and under the influence of environmental factors. The authors provide an overview of the state of the art of plant structure and function and how they relate to the mechanical behavior of the organism, such as the abi...
- 内容細目... Underpinnings of Cell Wall Mech......ctin chemistry and biomechanics: ......cal background and mathematical modelli......n as viewed by the creep method Tensile testing of primary plant cells and tissues.+- Wat......s Water motion and sugar transloc......lar mechanisms of mechanosensing and mechanotransdu......n Biomechanics and functional morphology of plants inspira......etic materials and structures.
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- 要約等This volume provides state-of-the-art methodology to functionalize microtubules and construct micr......pters consists of six sections d......g modification of microtubule structures, observation and control of microtubule mo......l applications of microtubules i......o, development of microtubule-bi......yze properties of microtubules, and functionalization of microtubules i......ls. Written in the highly success......troductions to their respective topics, lists of the necessary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known...... Authoritative and cutting-edge, Microtubules: M...
- 内容細目... in Biosensors and Bionanodevices......eous Alignment of Microtubules v......tern Formation of Active Matters......ing Biomimetic Structures Construction of Molecular Robo......ng Fabrication of Artificial Mus......ules, Kinesins and DNA Origami Nanostructures Encapsulation of Nanomaterials ...... Visualization and Quantification of Microtubule Se......al Deformation of Microtubules o......l-Time Imaging of Single [gamma]......on Systems for the High-Resolutio......tural Analysis of Tubulin-Ligand Complexes Cryo...... Visualization of Neuronal Parti......Reconstituting the Interaction Be......urified Nuclei and Microtubule Network Photocont...
- 件名Microtubules Nanostructured materials Nanomatériaux
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- 内容細目...ve Kinesiology of the Human Body Cop...... Contents List of contributors F......ents 1 History and basics of kinesiology 1 Past, present and future of kinesiology Hi......al perspective of the kinesiology st......es Development of kinesiology in......n 21st century and beyond Referen......s 2 Principles of kinesiology Ba......Cardinal plane and axes of motion Motion Mathematical fundamentals Units of measure Scalars and vectors Scalar...... Trigonometric functions Kinematics Ki......nt force Types of forces Gravity...... Torque Center of gravity Free b...... (acceleration and momentum) Thir......3 Fundamentals of human movement, its control a...
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- 内容細目...itive channels and transporters. History and perspectives of ion-transporti......insc / Hideki Kandori Channelrhod......l responses in the unicellular gr......i, Atsuko Isu, and Noriko Ueki Structure-function relationship of channelrhodops......ideaki E. Kato Functional mechanism of Cl⁻-pump rhodopsin and its conversion......tic modulation of ion channels b......isao Tsukamoto and Yuji Furutani ......ty, mechanism, and optogenetic application of light-driven i......tal properties and applications / Mineo Iseki and Sam-Yong Park ......tic potentials of diverse animal......masa Koyanagi [and 5 others] Molecular properties and o...
- タイトル標目Advances in experimental medicine and biology ; v. 1293
- 典拠情報（Author Heading/「を見よ」参照）Yawo, Hiromu Kandori, Hideki Koizumi, Amane Kag...
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- 要約等"The worldwide lead......ext on allergy and immunology. Th......ugh eight outstanding editions, M......y : Principles and Practice has been the reference of choice for both clinicians and researchers as......ical reference and an effective s......d preparation. The Ninth Edition continues the tradition of excellence wit......nsive coverage of all basic science and clinical appli......lergy practice and disease mechan......innovations in the diagnosis, prevention, and management of allergic disor......global issues, the advent of precision medicine, and new immunologic therapies. Offers unparalleled depth and up-to-date guidance on the fu...
- 内容細目... Immunobiology of IgE and IgE receptors ......uronal control of airway function in allergy Sec......B. Aerobiology and Allergens The structure and function of allergens Aerobiology of outdoor allerg......ns Preparation and standardization of allergen extra......ution : Indoor and outdoor Effect of the food matrix and processing on the allergenic activity of foods Section C. The Skin Structure of the skin and cutaneous immu......itis Urticaria and angioedema Her......ary angioedema and Bradykinin-med......mune complexes and allergic disease Section D. The Eye Allergic and immunologic diseases of the eye Section E. Respirator...
- 一般注記...y : principles and practice. Previous edition: P...
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- 要約等This book provides the readers with a......to-date review of the design, structure and function of a representative selection of fibrous protei......in both health and disease. The importance of the [alpha]-helica......motif based on the heptad repeat in the amino acid sequence of all [alpha]-fi......rous proteins (and parts of some globular ......to its design, structure, function and topology. Spec......ins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate f......myosin, fibrin and members of the spectrin super......teins based on the [beta]-pleated sheet and coll...
- 内容細目...a]-keratins in the epidermal appendages of birds and reptiles / R.D......ry Tropomyosin structure, function, and interactions: ......ha Barua Titin and nebulin in thick and thin filament ......Trinick Myosin and actin filaments in muscle: structures and interactions /......ris Dystrophin and spectrin, two ......imilar sisters of the same family / Olivier Delalande, Aleksander Czogalla, Je......s Hubert, Aleksander Sikorski [and others] Fibrin formation, structure and properties / J......tural proteins and their use in futur......ls / Tara D. Sutherland, Trevor D. Rap......rch Properties of engineered and fabricated silks / Gregor Lan...
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- 要約等The book deals wit......basic cellular and molecular mech......vely describes the important gene......c, biochemical and metabolic regu......lated diseases.The book is divide......or easy understanding. It takes the readers through the various aspects of aging in a sto......gular exercise and maintaining a balanced and peaceful life-......o suggested by the experts. The book would be ......researchers in the field. It woul......nical approach and policy making
- 内容細目...pter 1 Protein Structure and Function in Aging and Age-related Di......NA Replication and Aging Chapter ...... Transcription and Aging Chapter ......s, Translation and Aging Chapter 5 p53 and Aging Chapter ......iption Factors and Aging Chapter ......es, Telomerase and Aging Chapter 8 The Epigenome of Ageing Chapter...... Free Radicals and Reactive Oxyge...... 12 Stem Cells and Aging Chapter ......Autophagy Stop the Clock: Unravelling the Mystery in Dic......ing, Reasoning and Resolving Usin......M DURING AGING AND DISEASES Chapt......bolic Diseases and Aging Chapter ......s During Aging and Longevity Chapter 19 Protein ...
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- 要約等...ghly describes the fundamentals of a new multidis......iplinary field of study that aim......pen our understanding of the human body by ...... processing, mathematical analysis, and artificial int...... Anatomy (MCA) offers an advanced diagnosis and therapeutic naviga...... problems from the micro-level to......: space, time, function, and pathology. App......g this dynamic and living approach in the clinical setti......r planning for and more accurate, effective, and safe implementation of medical manage......ge processing, and biomedical eng......ed specialists and feature abunda......ons. Moreover, the findings presented here share...
- 内容細目...l applications of MCA to diagnos......1: Application of MCA across bio......: New Frontier of Technology in ......ional analyses of human organoge......nalysis during the human embryoni......sed Embryology and Embryo Imaging......h 15: Modeling of congenital hea......: New Frontier of Technology in ...... for measuring the 3D deformation of a multiphase structure to elucidate the mechanism of tumor invasion......: Construction of classifier of tumore cell types of pancreas cance......: New Frontier of Technology in ......8: Multi-modal and multi-scale im......perty analysis of brain tumor (T......s technologies and its application to medical im...
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- 内容細目...ichia coli for functional expression of membrane prote......brane complex: the functional SecYEG-SecDF......ase Expression of purification of OsVDAC4 Membra......ein expression and analysis in ye......ous expression of G-protein-coup......ted expression of GPCRs in insec......lls Expression of membrane proteins in the eyes of transgenic Dro......hod to express and purify human m...... protein using the Xenopus Oocyte system for functional and low-resolution......sis Expression of G protein-coup......s Construction of stable mammali......ble expression of G protein-coup......eceptors Rapid and facile recombinant expression...
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- 要約等"Physiology is the fourth volume in The Natural History of the Crustacea series, and the first book in ......de an overview of the comparative physiology of crustaceans. An understanding of physiology is ...... comprehension of the biology of this fascinati......ten by a group of internationall......g a wide range of crustacean taxa and topics, this volume synthesizes current research in a fo...
- 内容細目Endocrinology of molting / Simo...... Endocrinology of metabolism and water balance ......e color change and the molecular endocrinology of pigment transl......pbell McNamara and Sarah Ribeiro ......lograna Muscle structure, fiber types, and physiology / Scott Medler and Donald L. Mykl......ation, growth, and plasticity / D......nald L. Mykles and Scott Medler R......nny M. Hopkins and Sunetra Das Ci...... Iain J. McGaw and Carl L. Reiber......Osmoregulation and excretion / Je......-Hervé Lignot and Guy Charmantier Nutrition and digestion / Re......, temperature, and pH / Nia M. Whiteley and Edwin (Ted) W.......a : hemocyanin and hemoglobin / Nora B. Terwilli...
- 関連情報The natural history of the Crustacea
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- 内容細目BioID identification of lamin-associat......e Purification and structural analysis of LEM-domain pro......s Purification and structural analysis of SUN and KASH domain pr......- Purification and lamins and soluble fragments of NETs Simple separation of functionally distinct populations of lamin-binding ......ns Development of a novel green ......assay to study the association of plakins with i......ament proteins Functional analysis of keratin-associ...... intestinal epithelia: heat-shock......in chaperoning and kinase rescue Purification of protein chaperones and their functional assays with ......s Purification and structural analysis of plecti...
- 著者標目Wilson, Katherine L. Sonnenberg, Arnoud.
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- 内容細目...ology Overview of cellular physi......: touch, pain, and temperature Vi......& taste Reflex and voluntary control of posture & move......rical activity of the brain, sleep-w......Basic concepts of endocrine regu......mic regulation of hormonal functions The pituitary gland The thyroid gland The adrenal medull......rmonal control of calcium & phos......e metabolism & the physiology of bone Reproduct...... development & function of the female reproductive system Function of the male reproduct......stem Endocrine functions of the pancreas & regulation of carbohydrate m......olism Overview of gastrointestinal function & regulation Digestion, absor...
- ジャンル・形式用語Problems and exercises. Textbooks.
- 一般注記... is a revision of the original works of Dr. Francis Ganong."--Preface...
紙デジタル記事
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- 要約等...s (A 1-, A 2-, and DTNB-LC) were ......eletal muscles of eight marine teleosts and amino acid seq......ide sequences. The A1-LC from all......y conserved in their primary structures as in the case of DTNB-LC and contained a so......erence peptide of amino acid res......ich in alanine and praline in the N-terminal reg......2-LC. However, the N-terminal sequence of fish A 2-LC wa......alleye pollack and white croaker ......LC that lacked the difference peptide. On the other hand, A 2-LC from horse mackerel and mackerel-scad ......imilar to that of difference peptide, although their peptide length of about 10 residues was much sh...
- 件名cDNA cloning primary structure myosin light chain
- 参照A single locus in the mouse encodes ......light chains 1 and 3, a second lo......sible presence of the difference pep...... light chain 1 of fish fast skel......in Interaction of Alkali Light C...... Actin: Effect of Ionic Strength on the Cross-Linking of Alkali Light C......n 1 with Actin The primary structure of L‐1 light chain of chicken fast s...... muscle myosin and its genetic im......hysicochemical and immunological properties of myosin light chains from the ordinary muscle of marine teleost......s Light chains of carp and pike skeletal ......ins. Isolation and characterization of the most anodic li......it composition of fish myofibrils: The light ch...
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- 要約等The second edition of The Lung: Development, Aging and the Environment pr......ides an understanding of the multi-faceted nature of lung development, aging, and how the environment influences these processes. A......ry, pulmonary, and thoracic scientists and physicians it ......erface between the "normal and "disease cluster of chapters, allo......ement to each other. The interface betw......ases affecting the pediatric lung also adds a us...
- 内容細目Front Cover; The Lung; Copyrigh......al Development and Aging; Chapter...... Specification and Morphogenesis;......DUCTION; ONSET OF LUNG DEVELOPME...... ESTABLISHMENT OF PROXIMAL-DISTAL CELL FATE AND DIFFERENTIATIO...... 2 Development of Airway Epithelium; INTRODUCT......LL DEVELOPMENT OF AIRWAYS; SUBMUCOSAL GLANDS; EPITHELIAL DIFFERENTI......ON; REGULATION OF DIFFERENTIATIO...... 3 Development of the Innervation of the Lower Airways: Structure and FunctionINTRODUCTION; A......Y, MORPHOLOGY, AND DISTRIBUTION IN THE PRENATAL LUNG;......Y, MORPHOLOGY, AND DISTRIBUTION IN THE POSTNATAL LUNG; ONTOGENY AND REFLEX CONTROL OF AIRWAY SMOO...
- 件名...Lung Diseases--therapy Aging
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- 目次・記事...OGICAL ACTIONS OF CALCIUM/ 3 Andrew Fielding Huxley 2. PROFESSOR EBASHI'S JOURNEY TOWARD THE DISCOVERY OF TROPONIN: A PE...... 3. HIGHLIGHTS OF THE HISTORY OF CALCIUM REGULATION OF STRIATED MUSCL......ON BY TROPONIN AND TROPOMYOSIN 4. TROPONIN: STRUCTURE, FUNCTION AND DYSFUNCTION/ 21 Iwao Ohtsuki 5. FROM THE CRYSTAL STRUCTURE OF TROPONIN TO THE MECHANISM OF CALCIUM REGULATION OF MUSCLE CONTRAC......7 Yuichiro Maeda||Yasushi Nitanai and Toshiro Oda 6. CA ION AND THE TROPONIN SWITC......a V. Vinogradova||Deborah B. Stone||Galina G. Malanina||Robert A. Mendelson and Robert J. Flet......7. DISPOSITION AND DYNAMICS: INTERDOMAIN ORIENTA...
- 内容細目...gh Tropomyosin and troponin cooperativity on the thin filament ......ral transition of troponin in the complexes, on the thin filament, and in muscle fibr...... et al Crystal structures of tropomyosin by......ng tropomyosin and troponin regulations of muscle contraction and animal behavio...... al Structural and functional analysis of troponins from......allop striated and human cardiac ......cardiac muscle and disorders Cooperativity in the regulation of force and the kinetics of force development in heart and skeletal muscl......rfusion injury and cardiac tropon......nic mechanisms of cardiomyopathi......able biomarker of myocardial cell degradation b...
- 一般注記"Proceedings of the symposium enti......atory Proteins of Striated Muscle-Structure, Function, and Disorder (33rd NIPS Confeence...
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- 内容細目...Immunoglobulin structure and function Immune toleran......ion Chemokines The complement sys......ipid mediators of hypersensitivity and inflammation M......ecular biology and genetic engine......uction Biology of lymphocytes An...... cells Biology of mast cells and their mediators Biology of basophils Biology of eosinophils Biology of neutrophils Biology of monocytes and macrophages Airway epithelial cells Noncontractile functions of airway smooth ......athophysiology of allergic infla......ation Genetics and epigenetics in......ergic diseases and asthma Immunobiology of IgE and IgE receptors ......uronal control of airway function in allergy Re...
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- 要約等...dition fulfils the need for a sin......on resource on the etiology, path......sis, diagnosis and treatment of diseases of skeletal muscles, including the muscular dystr......nel disorders, and dysimmune myop...... background to the clinical cover......s in molecular and developmental ...... cell membrane and signal transduction science, and imaging techno......knowledge with the fundamentals of history-taking and clinical exami......continue to be the mainstay for p......ing physicians and biomedical sci......lar updates on the clinical and basic science aspects of muscle disease......y rising stars of myology - will be published o...
- 内容細目The scientific basis of muscle disease Structure and function of muscle fibres and motor units My......ls Biochemical and molecular basis of muscle disease Investigation of muscle Disease......cal evaluation of suspected myop......Histopathology and immunoanalysis of muscle Ultrastructural study of muscle Diagnostic imaging of muscle Description of muscle disease......eneral aspects The clinical assessment and a guide to classification of the myopathies The principles of molecular therapies for musc......es Description of muscle disease......ss Dystrophies and myopathies of early childhoo......hannelopathies and related disorders Inflammator...
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- 内容細目...cal properties of intermediate f......nal monitoring of keratin interm......cultured cells and tissues Phosph......nitbody probes of intermediate f...... modifications of intermediate f...... proteins Immunofluorescence and immunohistoche......ical detection of keratins - Hig......ament proteins The use of Withaferin A t......y consequences of cytoplasmic in......ent mutations: the case of epidermal kera......ng data mining and computational ......diate filament structure and function Isolation and analysis of keratins and keratin-associ......eins from hair and wool Skin keratins Simple epithelial keratins Methods for dete...
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- 内容細目The sarcomere and sarcomerogenes......lisabeth Ehler and Mathias Gautel......thryn N. North and Nigel G. Laing......Katarina Pelin and Carina Wallgre......osin, troponin and cofilin / Nigel F.......tigations into the pathobiology of thin-filament ......-Anh T. Nguyen and Edna C. Hardem......ent diseases / Anders Oldfors and Phillipa J. La......s / Bjarne Udd The Z-disk disease....../ Duygu Selcen and Olli Carpén In......ity : a matter of interlinking distinct structures via plectin /......tryk Konieczny and Gerhard Wiche The sarcomere and the nucleus : functional links to hyp......rophy, atrophy and sarcopenia / Mathias Gautel O...
- 一般注記...ted URL: Table of contents only http: //www.loc...