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- 内容細目...s Evolution of Proteins In Vivo / Alo......s for Directed Protein Evolution / So......ry Complements Protein Engineering / Tong Si, Pu ......s for Directed Protein Evolution / Ma......Reetz Rational and Semi-Rational Design. Data-driven Protein Engineering / Jonathan Gre......hilip A Romero Protein Engineering by Efficient S......cted Evolution and Computational ......ch Schwaneberg Engineering Artificial Met......Biotechnology. Protein Engineering Using Unnatura......Miguel Alcalde Engineering Antibody-Based......tics: Progress and Opportunities ......en Receptors / Andrew J Hou, Yvon......ng Tools Using Protein Engineering / Praopim Limsaku...
- 件名Protein engineering Protein engineering.
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- 要約等...f Cell Culture Engineering and Technology. It......of recombinant proteins, cell line de......, cell therapy and gene therapy, ......gn, monitoring and control and model-assisted......es for process design. The knowledge and expertise of t...... cell biology, engineering, biotechnology and biomedical sci......ctoral fellows and researchers in......pments in Cell Engineering
- 内容細目...eneration cell engineering using microRNA......proach towards engineering mammalian cell factories and bioprocesses f...... antibody glycoengineering for biopharmac......eneration cell engineering platform for i......ng recombinant protein production in ......ent stem cells and differentiated......rapy Scale-up (and scale-down) of......le Intensified and Continuous mAb......ess monitoring and control Industrial Monitoring...
- 件名Cell culture Genetic engineering Cells, Culture......lture. Genetic engineering.
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- 要約等...ensive methods and protocols about enzyme design. The chapters a......ry preparation and screening, sta......cted evolution and rational desig......sary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known...... Authoritative and timely, Enzyme Engineering: Methods and Protocols is a......oth the novice and the veteran researcher intere...
- 内容細目...nome Libraries and Screening for ...... Libraries for Protein Engineering toward Process......ons by 2GenReP and InSiReP Using ......ary History of Proteins to Engineer I......ion Expression and In Vivo Loading of De Novo Proteins with Tetrapyr......ational-Design Engineering to Improve Enz......ation to Guide Protein Engineering for Biocatalys......ents In Silico Engineering of Enzyme Acce......ons for Understanding Enzyme Dyna......tion Strategy, and an Improved Co......mical Reaction Engineering to Understand Applied Kinetics in Free Enzy...
- 件名...l applications Protein engineering Enzymes--Biote...... applications. Protein engineering.
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- 要約等...f cell culture engineering, providing insight into cell engineering, systems biology approaches and processing tec......n Cell Culture Engineering: Recombinant Protein Production, ed......s Gyun Min Lee and Helene Faustru......or therapeutic protein production; de......ream platform; and CHO synthetic ......ancing product and bioprocess att......sm; omics data and mammalian syst......usion culture; and much more. Thi......f cell culture engineering, including cell engineering, system biology approaches, and processing tec......ne development and cell engineering, e.g. via gene......ke CRISPR/Cas9 and with the aim to engineer glyc...
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- 要約等...aided antibody design. Chapters guide......body sequences and structures, mo......ody structures and dynamics, prediction and optimization of biological and biophysical pr...... interactions, and computer-aided......ity maturation and beyond. Writte......sary materials and reagents, incl......roubleshooting and known pitfalls, and step-by-step, ...... Authoritative and cutting-edge, ......to be a useful and practical guid......ew researchers and experts looking to expand their knowledge
- 内容細目Antibody sequence and structure anal......ng of Antibody and T Cell recepto...... for humanized and fully human th......ions Assessing and engineering antibody stabi......g experimental and computational ......ion Method for Protein Asparagine Dea......ope Prediction and Design for Ant......dy Development and Detection Info......o infection -- Protein-Protein Interaction Mo......iotherapeutic Candidates Structur......ional antibody engineering A computationa......ion sequencing and machine learning A computatio...
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- 内容細目...es, Occurrence and Biological Fun......stomer; Design and Production of ......lly Disordered and Resilin-based Protein Polymers for H......c Polypeptides and Elastometic Modular Protein-polymers: Amin......ional Ensemble and Stimuli-respon......als for Tissue Engineering; Biomimetic Ad......k-elastin-like Protein-based Polymers......ns; Processing and Properties of ......d B. Mori Silk and Recombinant Sp...... Based Fibres; Protein, Biomimetic Protein and Designer Protein Directed Synth......l Nanoclustres and Nano-bioconjugates and Their Potential Applications
- 件名Elastomers Proteins Biopolymers Élastomères Protéines Biopolymères elastomer protein
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- 内容細目...tricia Pereira and Christopher F. van der Walle Engineering thermobifida f......tic mechanisms and improved activ....../ Thu V. Vuong and David B. Wilso......lassifiers for protein classification / Loris Nanni and Alessandra Lumini Revolutionary protein engineering using molecula......oichiro Kodama and Seketsu Fukuza...... cyclophilin B and GP120 V3 loop / Alexander M. Andrianov and Ivan V. Anishc...... mechanisms of protein folding by mam...... ER chaperones and stress respons...... J. Geraldine Sandana Mala, Chellan Rose and Satoru Takeuchi Protein engineering of calcium binding proteins / Eugene A. Permyakov and Vladimir N. Uversky.
- 件名Protein engineering. Protein Engineering -- methods. Mo......ls, Molecular. Proteins -- chemical synthesis.
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- 要約等...d biomaterials and synthetic mate......cell functions and provide the ne......ials with cell and molecular biology and surveys how fu......d with spatial and temporal preci...... proliferation and phenotype in v......ell functions, and to redirect ce......nary research, and biomedical eng......logies in cell engineering that make poss......ling in cells, and light-induced ...... of stem cells and synthetic scaf......ryonic tissues and organs
- 内容細目...ence for organ engineering Generation of ......azuo Takayama, and Hiroyuki Mizug......ired materials and imaging Constr......tic systems in protein assemblies / Hiroyasu Tabe and Takafumi Ueno ......chine learning and Monte Carlo me...... the nanoscale and mesoscale leve......Endo Materials and chemicals for ......n / Ganesh N. Pandian and Hiroshi Sugiya...... nanoparticles and alternating ma......ko Ichivanagi, and Fuyuhiko Taman......rane potential and its environmen...... Motomu Tanaka and Akihisa Yamamo......ing stem cells and synthetic scaffolds to model ...
- 件名...als Biomedical and Dental Materials Stem Cells C...
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- 内容細目....4 Conclusions and New Perspectiv......Chapter 2 Keys and New Trends of ...... Catalysts as Candidates for Cata...... PO production and possible mecha......2.4 Conclusion and New Perspectiv......s by Combining Proteins and Organometallic......zymes by Using Protein Engineering Tools 4.2.1 Ar......rganometallics-Protein Conjugation 4.......ction 5.2 Heme Proteins 5.2.1 Heme gr......2.2 Hemoglobin and myoglobin 5.2.......l uses of myo- and hemo globin 5....... Non Heme Iron Proteins 5.3.1 Iron-sulfur proteins 5.3.1.1 Rubre......1.2.2 [Fe4-S4] and [Fe3-S4] type ......ron-Containing Proteins 5.4.1 Mononuc......5.5 Conclusion and Perspective Chapter 6 Fe-Cata...
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- 要約等This volume provides clear and direct protoco......iques to model and simulate biolo...... computational and experimental p......n from models, and how DNA parts ......ells to sense, and respond to, and intracellular ......sary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known...... Authoritative and cutting-edge, ......cuits: Methods and Protocols aims to ensure succ...
- 内容細目...ling, Analysis and Control of Syn......r-aided Design and Pre-validation...... Genetic Parts and Devices using ......gn for Systems and Synthetic Biol...... Gene Networks Engineering Sensors for Ge......ression Burden Engineering Protein-based Parts for Genetic Devic...
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- 内容細目Front Cover; Peptide, Protein and Enzyme Design;...... Conjugates as Protein Modification C......2.2. Materials and General Consid...... an SH3 Domain and Gel-Based Visu......3.2. Materials and General Consid......Preparation of Protein Modification B......(II)-Catalyzed Protein Modification; ...... Alkyne-Tagged Protein by Chemical Bl......he Affinity of Protein-Protein Interactions: Technologies and Considera ... ......Binding Theory and Relevance of K......brium; 3.2. Ligand Depletion; 4. ......1.2. Solutions and Media; 4.1.3. Proteins/Antibodies 4.......xclusion Assay and Surface Plasmo......Chapter Three: Protein and Antibody Engineering by P...
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- 内容細目Computational design of novel protein binders and experimental a......, David Baker, and Sarel J. Fleis......y / Jian Zhang and Gevorg Grigory......Ariel Erijman, and Julia M. Shifm......thods to model and design protein alternative co......mes S. Fraser, and Tanja Kortemme Osprey : protein design with en......, flexibility, and provable algor......l Reza, Amy C. Anderson, David C.......S. Richardson, and Bruce R. Donal...... improvement / Andrew Leaver-Fay,......n W. Davis, Roland A. Pache, Serg......, David Baker, and Brian Kuhlman ......g, evaluation, and refinement of ......nally designed proteins / Gert Kiss, Vijay S. Pande,...
- 件名Protein engineering. Protein Engineering.
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- 要約等...ferent aspects and applications o......struct design, and multiplex clon......ems, metabolic and signaling pathways, advanced engineering of metabolic n...... of organelles and co-culture of ......icroorganisms, and methods for the on command manipulation o......e stability of proteins. Written in t......sary materials and reagents, incl......roubleshooting and known pitfalls, and step-by-step, ...... Authoritative and cutting-edge, ......ology: Methods and Protocols aims...... willing to expand their portfolio of tools and strategies
- 内容細目...r plant genome engineering using the Gold......DNA assembly standard pSHDY - a n......ol for genetic engineering of cyanobacter......Cas9 ribonucleoproteins Coexpression and reconstitution......aging to study protein-protein interaction and complex format......r the assembly and expression of ......t Mitochondria Engineering destabilizing ......thetic Biology and Molecular Farming
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- 要約等...al solid waste and algal blooms. ......biorefineries, and the hydrotherm......s, researchers and engineers work...... environmental engineering, wastewater ma......ment, chemical engineering and related areas
- 内容細目... in Bioprocess Engineering 1 Introduction......Membrane Types and Their Importan......Pharmaceutical and Biotechnology ......on 3.3 Racemic and Azeotropic Sep......Industries 4.1 Protein Purification and Concentration ...... 4.3 Skim Milk and Cheese Product......ation 4.5 Beer and Wine Productio...... in Bioprocess Engineering 5.1 Artificial......rences Process Engineering Aspects in Bio......very 3 Process Engineering Aspects in Bio...... Inoculum Size and Growth 3.1.3 O......-Waste Loading and Particle Size ......reactor Design and Its Operationa......Soil for Metal and Organic Pollut......nmental Toxins and Contaminants 1.2 Contaminants...
- 件名...ental science, engineering & technology. ....... Technology & Engineering--Environmental....... Technology & Engineering--Power Resources--Alternative...
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- 要約等...ign, structure and function of a ......ion of fibrous proteins in both health and disease. The i......alpha]-fibrous proteins (and parts of some globular proteins) is underline......ture, function and topology. Specific proteins covered in the text and which depend o......heir structure and function, incl......diate filament proteins, tropomyosin,......myosin, fibrin and members of the......ed are fibrous proteins based on the ......-pleated sheet and collagen confo......ant structural proteins, especially of silk and collagen, are ......ed researchers and postgraduate s...... the fields of protein chemistry, biochemistry and s...
- 内容細目...Trinick Myosin and actin filament......le: structures and interactions /......ris Dystrophin and spectrin, two ....../ Olivier Delalande, Aleksander Czogalla, Je......s Hubert, Aleksander Sikorski [and others] Fibrin......ion, structure and properties / J......ant structural proteins and their use in f......Tara D. Sutherland, Trevor D. Rap...... of engineered and fabricated silks / Gregor Lan...
- 件名Proteins. Collagen. Scleroproteins--chemistry. Scleroproteins--physiology.
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- 要約等...aracterization and application in biology and medicine provi......rization tools and applications o...... biomaterials, and compiling the ......ving organisms and intrinsic to b......cal structures and function. Not ......iting field of engineering artificial sel......nguage of life and can be designe......ffering unique engineering opportunities ......ecific methods and techniques to ......t, investigate and characterize self-assembly and formed assembl...... length scales and the nano/micro......, cell culture and tissue regeneration. Written ...
- 内容細目...ecent progress and the future / S......led mechanical and biological per......b Elastin-like proteins: Molecular de......Soraya Salinas and Marcos Herrero......ognition / Alexandra Brito, Rui L......cardo A. Pires and Iva Pashkulvea...... self-assembly and opportunities ......c biomaterials and biointerfaces ......Jelena Jeftić and Thierry Benveg......Stephanopoulos and Ronit Freeman ......dopyrimidinone and benzene-1,3,5-......rten H. Bakker and Patricia Y.W. ......Joseph L. Mann and Eric A. Appel ......el K. Grötsch and Job Boekhoven ......plex structure and dynamics in su...... Feiner-Gracia and Lorenzo Albertazzi Probing lo...
- 一般注記...f contributors and their associations. Woodhead ...
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- 内容細目...he development and production of ......tibodies using protein engineering tools Material and methods of bac......s : production and action Synthetic biology and metabolic engineering approaches for......ved production and recovery of ba......r-based micro- and nanofibers fab......ed surfactants and biosurfactants......haracteristics and applications of biodiesels and design of reac......er remediation and photobiocatalysis.
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- 要約等...or identifying and studying the v......r the analysis and practical use ......sary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known...... Authoritative and practical, Ant......lants: Methods and Protocols serv......ral production and beyond.
- 内容細目Identification and Functional Ana......Genes-Overview and Functional Analysis of Candidate Genes Ins......rus Resistance Protein Reverse geneti......ance signaling and the resistance......a benthamiana Random Mutagenesis ......or Positive-strand RNA Viruses fo......Identification and Characterizati......Products Plant Protein-Mediated Inhib......tern Screening and Biological Ana......sis of a Plant Protein Interacting wi......Viral Movement Protein- Transfection ......g rgs-CaM-like Proteins in Transgenic......vel Components and Regulators of ......ign, Synthesis and Functional Ana......le Inoculation and Evaluation Methods for Attenu...
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- 要約等... in the active and exciting field......s fundamentals and comprehension ......l as materials and cuttingtechnol......aracterization and underpin their biomedical app...
- 内容細目...es; Biomimetic and Collagen-based......lds for Tissue Engineering Strategies; Protein Aggregation Suppression and Folding Promot......s; Bioinspired and Bioinstructive...... Microfluidics and MOFs; Soft Fib......deling; Animal Protein-based Soft Mat......als for Tissue Engineering Applications; Soft Robotics S...
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- 内容細目...iboswitches Ligand-dependent expo...... modular "plug-and-play" expressi......boswitches for engineering novel genetica......es Integrating and amplifying sig...... transcription Engineering of ribosomal s......correlate mRNA and protein levels in Esch......onitoring mRNA and protein levels in bulk and in model vesic......ign, synthesis and application of......riggered by strand displacement U......ene expression and define gene fu......ces coelicolor Engineering of ribozyme-ba...... for metabolic engineering Riboselector: ......itoring RNA-ligand interactions and riboswitch-tar......boswitch drug candidates.
- 件名RNA. RNA-protein interactions. ......senger RNA. Ligands (Biochemistry) Riboswitches....