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- 要約等...algae, photosynthetic bacteria, synthetic construct d......ltiple aspects of synthetic metabolic, photosynthetic systems, me......ed engineering of metabolic netw......rks, isolation of organelles and co-culture of microorganisms......nd methods for the on command manipulation of the relative stability of proteins. Written in the format of the highly successful Methods in Molecular Biology series, each c......ntroduction to the topic, lists n......edge, Plant Synthetic Biology: Methods and P......ling to expand their portfolio of tools and strategies
- 内容細目Heterologous production of plant terpenes in the photosynthetic bacterium R......sulatus Design of multiplexing C......ineering using the GoldenBraid DN......a new tool for genetic engineering of cyanobacteria ......d targeted mutagenesis in plants Generation of stable, light-......en co-cultures of cyanobacteria ......ophic microbes Gene editing in gre......reconstitution of enzymatic casc......er toolbox for the assembly and expression of multiple trans......psis seedlings Genetically-encoded......biosensors for the quantitative analysis of auxin dynamics......lls Exploiting the Gal4/UAS syste......ant orthogonal molecular toolbox to control reporter e...
- 件名Plant gene expression Plant genetic transformation Synthetic Biology Biologie synthétique Plantes-......otechnology Synthetic biology
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- 要約等"Over the past forty years a molecular vision has transformed biology. What began as......t organisms at the microscopic le......el soon led to the rapid development of pathbreaking n...... understanding of science. In The Black Box of Biology Michel Morange......transformation of biology was not an accumulation of new results, but the molecularization of a large part of biology. The expansion led to a cluster of explanatory to......ms used across biology and medicine. Yet, it was the fusion of the principles and concepts of molecular biology with those of other subdisciplines that led to the most decisive ......ges, including the discoveries of regulatory RNA...
- 内容細目...tein structure The rise of developmental biology Molecular biology and evolution Gene therapy The central place of RNA Epigenetics Sequencing the human genome Systems biology and synthetic biology Images, repres......d metaphors in molecular biology
- 件名Molecular biology--History SCIEN......ife Sciences / Biology / Molecular Biology. Molecular biology. Molekularbiologie Molecular Biology--history
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- 要約等...ume expands on the previous editi...... to chemistry, biology, physiology, p......d pharmacology of CCN proteins. The chapters in th......h as CCN4 immunofluorescence for......ilizing public molecular biological dat......mily research; the effects of CCN4 on pancre......proliferation; gene expression analysis of CCNs; novel ce......ing activities of CCN proteins; and the function of CCN2 in tubular epithelium cells with...... on renal fibrogenesis. Written in the highly successful Methods in Molecular Biology series format,......troductions to their respective topics, lists of the necessary mate......tarting out in the field of CCN research
- 内容細目...rch Evaluation of the Effects of CCN4 on Pancre......ation Analysis of CCN Functions in Liver Regeneration After Pa......al Hepatectomy The Evaluation of Meniscus Regenerative Effects of LIPUS-Induced ......ction by LIPUS of CCN2 and Meniscus-Related Genes in Cultured M......ssues Analysis of Chemotactic Property of CCN2/CTGF in I......embranous Osteogenesis Novel Cell ......ing Activities of CCN Proteins I......aging Analysis of Neurotrophic E......ent Stem Cells Gene Expression Analysis of CCNs Along wit......n In Vivo Angiogenesis Assays for the Analysis of CCN Proteins Using the Bleomycin-Induced Model of Fibrosis to Study the Contrib...
- タイトル標目Methods in molecular biology (Clifton, N.J.) ; v. 2582 Spr...
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- 要約等...ume expands on the previous editi......h an update on the latest techniq...... plant systems biology on three specific scales: the molecular level, the tissue level, and the whole plant. C......topics such as gene regulatory net......will induction of plant aerial o......quantification of tissue mechani...... properties; mathematical modeling of plant tissue u......MS. Written in the highly successful Methods in Molecular Biology series format,......troductions to their respective t...... protocols or software tutorials......Plants Systems Biology: Methods and P......g solutions to their questions and generating new ideas, as well as f...
- 内容細目... How to Define the Appropriate Sp......ial Resolution of Root Segments ...... Plant Systems Biology Plant Systems Biology: Further Reading and Resources
- 件名Plant molecular biology Systems biology Systems Biology Biologie moléculaire végét...
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- 要約等...(DBTL) into synthetic biology research. Chap......ms, setting up of an automated b......equencing, microfluidics -using ......lar signals in general. Written in the highly successful Methods in Molecular Biology series format,......troductions to their respective topics, lists of the necessary mate......tting-edge, Synthetic Gene Circuits: Meth......ful results in the further study of this vital field
- 内容細目...is and Control of Synthetic Regulatory ......cal Simulation of Gene Circuits Using......(Re-)Design Synthetic Circuits Au......Pre-validation of Large Batches of DNA Assemblies......d Planning for the Verification of Large Batches of DNA Constructs......Characterizing Genetic Parts and D......tate Cell-Free Gene Expression with Microfluidic Chemostats A Microfluidic/Microsco......hip Controlled Gene Expression in ......Systems and Synthetic Biology Using Amigo A ......ion Prediction of cellular burde......troactivity in Gene Networks Engin......ng Sensors for Gene Expression Bur......ased Parts for Genetic Devices in Mammalian Cells
- 件名Synthetic biology--Laboratory manuals Gene Regulatory Networks Synthetic Biology--methods Synthetic biology.
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- 要約等...ble compendium of up-to-date methods in the fields of environmental toxicology, molecular toxicology, an......ajor sections, the volume examine......city, applying the Ames assay to ......s divided into these parts, the methods can be......s. Written for the highly successful Methods in Molecular Biology series, chapte......troductions to their respective topics, lists of the necessary mate......e resource for the scientific com......re research in the vitally important field of environmental toxicity, molecular toxicology, and toxicogenomic...
- 内容細目Detection of Caenorhabditis...... Toxic Effects of Metal Mixtures......ns Evaluations of Environmental ......thods to Assay the Behavior of Drosophila mel...... Investigating the Joint Effects of Pesticides and......us laevis and Other Amphibians Identification of Stable Reference Genes for Toxicogenomic and Gene Expression Ana......hod to Explore the Regulation of Gene Transcription ...... Mice Analyses of Epigenetic Modificatio...... Neurotoxicity The Application of Omics Technologies in the Research of Neurotoxicology Flow Cytofluorometric Analysis of Molecular Mechanisms of Premature Red ......in Liver Cells of the Tilapia Fish Oreochromis ...
- 件名Environmental toxicology Genetic toxicology
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- 要約等This book expands upon the useful first e......ll as a number of recently devel......ications. With the changes in ins......l advances and the development of new reagents t...... legal issues, the qPCR field is ......s. Written for the highly successful Methods in Molecular Biology series, chapte......troductions to their respective topics, lists of the necessary reag......nd vital field of study
- 内容細目A Quarter Century and the PCR Applied Techniques and the Fields of Use Are Still ......ant Validation of MicroRNA Bioma......Quantification of MicroRNAs Usin...... PCR Detection of Yellow Fever V......CR) Evaluation of the Abundance of Fungi in Waste......arly Detection of Fungal Plant P......ntitative PCR: The Case of Diplodia sapinea on Pine A General Protocol for Accurate Gene Expression Ana......ysis in Plants Gene Expression Ana......aracterization of Circulating Tu...... Real-Time PCR Molecular Monitoring of Chronic Myeloi......plications for the Determination of the Biological Age......Genotyping and Gene Expression Analysis Digital P...
- 件名Genetics Human genetics Genetics. Human genetics.
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- 要約等Chapter “Alignment of Biological Sequences with Jal...
- 内容細目The Clustal Omega ......SE Cooperation of Spalm and Prrn......r Construction of Gene-Structure-Awar......putation using the T-Coffee Regressive ......or Large Heterogeneous Datasets us......out Alignment: The SpaM Approache......ensus Sequence of Long Reads Automated Removal of Non-Homologous......EQUAL Analysis of Protein Intermolecular Interaction wi......matic Analysis of Protein Superf......lies Alignment of Biological Seq......Multiplatform Software for Multi......nce Alignment, Molecular Phylogenetic Analyses, a......ench: Desktop Software for Compa......ing Evaluation of Multiple Sequence Alignment M...
- タイトル標目Methods in molecular biology (Clifton, N.J.) ; v. 2231
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- 要約等... explores rice molecular biology, genetic engineering......o three parts, the book covers subjects such as genetic engineering......tissue culture of rice, includin......ormation and regeneration, genome ......tegration, and gene stacking in ri......s for targeted gene knock-out or g......bioinformatic, molecular, and cellular ......e. Written for the highly successful Methods in Molecular Biology series, chapte......troductions to their respective topics, lists of the necessary mate......ngineering and Gene Editing: Metho......striving to further their efforts on a...... and producing genetically improved rice varietie...
- 内容細目Gene assembly in Ag......(GAANTRY) TransGene Stacking II ve......neering and synthetic biology Morphogenic regulators and their application ......transformation of rice by hygrom......ferase (hptII) gene containing CRI......-independent regeneration and tran......and assessment of BE3 and Target......Genome editing of rice by CRISPR...... rice Analysis of off-target mutati......n rice by multigene editing with C...... site-specific gene integration in rice Rice gene targeting by h......egy Prediction of rice transcrip...... isolation and gene expression ana......ation analysis of C4 proteins in the leaf tissue of rice Selection...
- 件名Rice--Genetic engineering Rice--Molecular aspects Botany Microbiology Genetics Botany. Genetics. Microbiology. Rice--Genetic engineering.
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- 要約等This book provides state-of-the-art information on gene essentiality s......a wide variety of organisms, i.e......protein-coding genes and other genomic eleme......ith a focus on the two techniques......revolutionized the field, the collection beg......so delve into other techniques fo......ring essential genes, such as bioi......s. Written for the highly successful Methods in Molecular Biology series, chapte......troductions to their respective topics, lists of the necessary mate......ive, Essential Genes and Genomes: ......pting to strip genetics down to its fundamentals
- 内容細目A Method to Map Gene Essentiality of Human Pluripot......ally Essential Genes in Human Cell......Identification of Small Molecule......CRISPR-Cas Mutagenesis Scanning of Essential Genes Design and Generation of a CRISPR Inter......nce System for Genetic Repression and Essential Gene Analysis in the Fungal Pathoge......Identification of Essential Genes Using Sequent......AID to Quickly Generate Conditiona...... for Essential Genes in Various Ve......onal Mutations of Essential Genes in Cyanobacteria A Method of Transposon Ins......rio vulnificus Genes Required for ......in Human Serum The Use of Tn-Seq and the FiTnEss Analys...
- 件名Genes Genomics Gene editing Gènes Génomique Édition génique Gene editing. Genes. Genomics.
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- 要約等...ive collection of state-of-the-art protocols ......ular dystrophy therapeutics, covering therapeutics using......gonucleotides, gene replacement, g...... by leaders in the field, the volume explore......ng an exciting therapeutic revolu......phy. As a part of the highly successful Methods in Molecular Biology series, chapte......troductions to their respective topics, lists of the necessary mate......ular Dystrophy Therapeutics: Meth......to develop new therapeutic techno......for this group of diseases
- 内容細目Current Strategies of Muscular Dystrophy Therapeutics: An Overview The Story of Viltolarsen: F......Rapid Freezing of Skeletal and C...... Histological, Genetic, and Protei......e Pathology in the D2/mdx Mouse M......ssociated with the Quantification of Utrophin Physi......cal Assessment of Muscle, Heart,......dy Function in the Canine Model of Duchenne Muscu......53 Skipping in the DMD Gene in Immortalize......ive Evaluation of Exon Skipping ...... Dystrophy Use of Glycine to Aug......pping and Cell Therapies for Duch......gated PMOs for the Treatment of Myotonic Dystr......phy Developing Therapeutic Splice-Correcting Ant...
- タイトル標目Methods in molecular biology (Clifton, N.J.) ; v. 2587 Spr...
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- 要約等...ume expands on the previous editi......topics such as gene suppression, e......mming; cardiac gene therapy vectors an......oters; cardiac gene delivery metho...... and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format,......troductions to their respective topics, lists of the necessary mate......nsive, Cardiac Gene Therapy: Methods a......are conducting gene therapy research. ......ill lead to further advancements ......ranslations in the field
- 内容細目Updates on Cardiac Gene Therapy Research a......hods: Overview of Cardiac Gene Therapy Tough Deco......diated Cardiac Gene Suppression Di...... Reprogramming of Adult Human Ca......bo CRISPR/Cas9 Gene Editing of RYR2 in Human ......ng Aberrancies of CPVT Arrhythmogenesis Enhancing C......diated Somatic Gene Editing for Ca......l Optimization of Synthesis of Modified mRNA ......and Production of Heart Chamber-......c AAV9 Vectors Generation of Atrial-Specifi......n Rats Cardiac Gene Delivery in La......c Acid AntimiR Therapy for the Heart Cardiac Gene Delivery in La......on Endocardial Gene Delivery using NOGA Catheter System Surgical Methods fo...
- 件名...tem--Diseases--Genetic aspects Genetic vectors Genetic Therapy--methods Heart Diseases--therapy Gene Transfer Techniques Genetic Vectors Car......tem--Diseases--Genetic aspects.
Solanum tuberosum : methods and protocols (Methods in molecular biology ; 2354) (Springer protocols)
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- 要約等This volume offers a comprehe......ive collection of experimental a......ons covering a general overview of potato, the research fields of molecular biology, omics approac......, and finally, the application of the generated knowledge......nt. Written in the format of the highly successful Methods in Molecular Biology series, each w......ntroduction to the topic, lists n......e a collection of methods for the potato researc......n insight into the world of the potato
- 内容細目Importance of Potato as a Cr......yopreservation of Potato Shoot T......phering Potato Molecular Response Yeast......Identification of Protein-Protei...... with Modified Gene Functions in R......Identification of Transcription ......ric Monitoring Of Plant Hormone ...... visualization of RNA-seq data u......Identification of Resistance Genes Using Diagnostic R-gene Enrichment Seq......Quantitative Profiling of sRNAs in Potat......ds Quantifying the contribution to virulence of Phytophthora i......Identification of Solanum immune......nant Screening Gene editing in pot......as9 technology Gene downregulation......bacterium rhizogenes-mediated Transformation Mole...
- タイトル標目Methods in molecular biology (Clifton, N.J.) ; v. 2354 Spr...
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- 要約等...enzyme design. The chapters are g......reening, state of the art techniques......ed by examples of immobilization of enzymes on sus......s. Written for the highly successful Methods in Molecular Biology series, chapte......troductions to their respective topics, lists of the necessary mate......guide for both the novice and the veteran researcher interested...
- 内容細目Preparation of Soil Metagenom...... Screening for Gene Specific Ampli......hput Screening of Metagenomic Li......ng Droplet Microfluidics Synthetic DNA Librari......ent in Drug Synthesis In Silico P......Saturation Mutagenesis Recombination of Compatible Sub...... InSiReP Using the Evolutionary History of Proteins to En......Representation of Ancestral Sequ......n Vivo Loading of De Novo Protei...... Tetrapyrrole Cofactors Rational......Improve Enzyme Thermostability Using Molecular Simulation to ......co Engineering of Enzyme Access ......tum-Mechanical/Molecular-Mechanical (QM......d an Improved Cofactor Co-Immobilization Techni...
- 関連情報Methods in molecular biology
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- 要約等This volume details generation of gene-edited cell li......eaders through gene regulation, ed......ing, screening of cell lines, ge......nd an overview of the tools for effi......PR. Written in the format of the highly successful Methods in Molecular Biology series, each c......ntroduction to the topic, lists n......, Applications of Genome Modulat......nce or advance their study in this field
- 内容細目...ISPR Efficient generation of stable cell li...... neuronal transgene expression using the piggyBac trans......ecific editing of the genome in Plur......ells Targeting the AAVS1 site with transgene cassette by CR......inducible transgene cassette for the to neuronal differentiation of human pluripot......Microinjection of zygotes for CR......ated insertion of transgenes into the murine Rosa26 ......ous activation of SMARCA4 expres......CRISPR/Cas mutagenesis to generate novel trai......ome Editing in the New World Scre...... Sheep Blowfly Generation of gene drive mice for......on suppression Generation of a human deafness she...
- 件名Gene editing--Laboratory manuals Gene editing
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- 要約等...es. Written in the highly successful Methods in Molecular Biology series format,......troductions to their respective topics, lists of the necessary mate......various fields of molecular biology, including biotechnology, molecular genetics, and recombinant DNA tech...
- 内容細目The significance of PCR primer design in genetic diversity s...... research into the genetic structure of marine species......elegans Design of oligonucleotid...... on PCR and isothermal techniques Detection of rubella virus ...... RT-PCR Design of mismatch prime......application to the authentication of meat products ......mer design for the analysis of closely relate...... - application of non-coding mtD......CR primers for the amplification-......tem Validation of circular RNAs ......Identification of gene copy number in the transgenic pla......mer design for the rapidly evolvi...... for detection of novel plant capsid-less virus...
- 件名Polymerase chain reaction Gene amplification ......N polymérases Gene amplification. Polymerase cha...
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- 要約等...eat deal about general aspects of molecular and cellular s...... and function. Molecular and Cellular Biology of Viruses leads ......an exploration of viruses by sup...... learning. All the major classes of viruses are co......e chapters for their replication ......re independent of the virus genome t......ngagement. End-of-chapter questi......being given on the website (half ......ples come from the most-studied a......also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay betw......e development. The final chapter is on virus div...
- 内容細目The fundamentals of molecular and cellular virology The virus replicat...... and uncoating Gene expression and......bacteriophages Gene expression and......replication in the positive-strand RNA viruses Gene expression and......replication in the negative-strand RNA viruses Gene expression and......replication in the double-stranded RNA viruses Gene expression and......replication in the double-stranded DNA viruses Gene expression and......replication in the single-stranded DNA viruses Gene expression and......replication in the retroviruses a...... Viral evasion of innate host de...... Viral evasion of adaptive host defenses Medica...
- 件名Molecular virology Cytol......tions Viruses--genetics Gene Expression Reg......iral Cytology. Molecular virology. Cytologe Cytologie ...
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- 要約等"Now in its fourth edition, Molecular Hematology has......nt advances in molecular research. The aim of the book remains the same --^ to pr......le exposure to molecular biological techniques. Molecular biology has had a sign......cant impact on the understanding of blood diseases......book shows how molecular techniques can......n each chapter the authors summarize the impact made by molecular research on the understanding of the pathogenesis of the disorder featu...... and highlight the molecular strategies tha......estigated, for therapeutic purpos......s designed for the non-specialist......More than any other discipline, hematology relie...
- 内容細目...Tomas Ganz The molecular basis of iron metabolis......& Steven Okoli Molecular pathogenesis of malaria / Davi......tan E. Chitnis Molecular coagulation an......ndreas Hillarp The molecular basis of hemophilia / D.......F. Giangrande The molecular basis of Von Willebrand......h J. Clemetson The molecular basis of blood cell all......rown Functions of blood group an......John W. Semple Molecular therapeutics in hematology : gene therapy / William ......nd development of molecular biology / Paul Moss Ca......minique Bonnet Molecular basis of transplantation / Francesco D...
- 件名Hematologic Diseases Molecular Biology--methods
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- 要約等...an be used for generation of knockout anima......Chapters guide the reader through......al. Written in the successful Methods in Molecular Biology series format,......troductions to their respective topics, lists of the necessary mate......hes to help further their study in this field
- 内容細目Construction and Evaluation of Zinc Finger Nu......dated overview of TALEN construc......or Enhancement of a Target Gene Expression by ......eriment design Generation of genome-edited ......smic injection of CRISPR-Cas9 RNA Gene targeting in m......genome editing Generation of Knock-in Mouse......g Introduction of genetic mutations i......lectroporation Generation of floxed mice by......ient detection of flox mice usin......sisted Knockin of Large DNA Dono......Genome editing of murine liver h......ted expression of Cas9 in vivo N......Genome editing of rat A simple a......ent method for generating KO rats ......ocytes Editing the Genome of the Golden Hamster ...
- 件名Animal genetic engineering......sgenic animals Gene editing Genetics--Technique Animal genetic engineering. Gene editing. Genetics--Technique. Transgenic an...
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- 要約等"In science and technology, the images used to......d explosive as the concepts and processes they embody--both works of art and generative forces in their own right. D......alogue between the histories of art, science, ......nd technology, The Technical Image explores these images not a......yered elements of the process of generating knowledg......ole in shaping the findings and insights they illustrate, b......chers' choices their appearances may be--how they come to embody the styles of a period, a mi......ing with a set of key questions ...... and medicine, The Technical Image then investigates ......atson's models of genes, drawings of Darwin's f...
- 内容細目... image series: the project "technik im bild" at the Deutsches Muse......techniques. In the eye of the beholder: Eman......apparatuses at the international ......adow image: on the specificity of early radiographs and their interpretati......ded vision and the imagination: the migration of worms and drag......mages: systems of notation in se...... modern images of musical automa......templations in the Quirinal garde......e. Drawing and the contemplation of nature: natura......y around 1600: the case of Aldrovandi's images / Angela ...