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- 内容細目...eases: repurposing knowledge, mechanisms and therapeutics to increase discover......y / David C. Swinney, Michael P....... of zika virus infection: lesson......aul C. Jordan, Andreas Jekle, Jer......e Deval Developing therapeutics ......rickson, Christina F Spiropoulou Part II. Kinetoplastids. Designing drugs to targ...... disease: when chemistry needs biology / Martine Keenan, Eric Chatelain Drug discovery and development fo......panosomiasis / Andrew Spaulding, Mitchell F. Gallerstein, Lori Ferrins Discovery of ......s report / Baljinder Singh, Frederick S...... Part III. Helminths. Onchocerci......wryluk, Ivan Scandale Drug discovery and develop...
- 件名Tropical medicine. Drug development. Tropical Medicine. Drug Development.
- タイトル標目Methods and principles in medicinal chemistry ; v. 77.
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- 内容細目Pt. 1. Principles pt. 2. Data pt. 3. Methods pt. 4. Applications.
- 件名Pharmaceutical chemistry.
- 著者標目Brown, Nathan (Medicinal chemist)
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- 内容細目In vitro characte......mall-molecule kinase inhibitors Screening for kinase inhibitors: from ...... assays Dissecting phosphorylati......gue-sensitive kinases and more specific kinase inhibitors as too......rug design of kinase inhibitors for si......ction therapy Kinaes inhibitors in signal transdu......therapy Design principles of deep pocket-targeting protein kinase inhibitors From discovery to clinic: aurora kinase inhibitors as nov......ncer Discovery and design of protein kinase inhibitors: targeting the cell cycle in oncology Medicinal chemistry approaches for the inhibition of the...... Cellular protein kinases as antiviral targets ...
- 件名Protein Kinase Inhibitors -- the......iscovery. Protein kinases -- Inhibitors. Antineoplastic agents -- Developmen...
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- 件名Biological Products--chemistry. Biological Pr......Pharmaceutical chemistry. Naturstoff Pharmazeutische C...
- タイトル標目Methods and principles in medicinal chemistry ; v. 60.
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- 要約等...rs key aspects in early drug dev......iscovery phase and are required for first-in-human studies....... broad scope brings together cri......om many disciplines, ranging from process ......harmacology to intellectual prop...... issues. After introducing the overall e...... are described in a sequential and enabling order: the av......drug substance and that of the dr......on of pharmacokinetics and -dynamics, as ......g safety. The final section focuses on intellectual prop......rty aspects during early clinical developmen......lify salient points, resulting in an abundance o......ctice-oriented information that is usually not ...
- 件名Drug development. Drugs--Testing. Clinical trials. Human experimentation in medicine.
- タイトル標目Methods and principles in medicinal chemistry ; v. 73.
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- 件名Combinatorial Chemistry Techniques. Microwaves. Chemistry, Organic. Chemistry, Pharmaceutica......Pharmaceutical chemistry. Organic compounds--Synthesis...
- タイトル標目Methods and principles in medicinal chemistry ; v. 52.
- 著者標目Kappe, C. Oliver. Stadler, Alexander, 1973- Dallinger, Doris.
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- 件名Protein drugs. Proteins--Therapeutic use.
- 関連情報Methods and principles in medicinal chemistry
- 掲載誌Methods and principles in medicinal chemistry
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- 件名...sign. Pharmacokinetics. Drugs--Metabolism. Drug...
- タイトル標目Methods and principles in medicinal chemistry ; v. 51.
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- 内容細目v. 1. Alphabetical listing v. 2. Appendices, references...
- 件名Drugs -- Design. Cheminformatics. Drug Design -- Handbooks. Models, Molecular -- Handbooks. Molecula......nformation -- Handbooks. Pharmacology, Clinical -- Handbooks. Molecular pharmacology.
- 一般注記Updated ed. of: Handbook of molecular descriptors,...
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- 一般注記...r biographical information http: //www.loc.gov/...
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- 内容細目Volume 1. General principles of supramolecular chemistry and molecular reco....... Experimental and computational methods in supramolecular chemistry / volume edito......n Volume 4. Bioinspired and biomimetic supramolecular chemistry / volume edito......wickramarajah, Andrew J. Wilson V......Supramolecular medicinal chemistry and chemical biolo......olume editors, Andrew J. Wilson, ......ramolecular engineering : discrete mo......ramolecular engineering : designing the solid sta......escent sensors and imaging agents / volu......ume editor, Colin Raston.
- 件名Supramolecular chemistry. SCIENCE / Chemistry / Physical & Theoretical
- 並列タイトル等（連結）Comprehensive supramolecular chemistry 2
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- 内容細目Front Matter Introduction. His......e / ROBERTA S KING Factors Affecting Metabolism / ROBERTA S KING Biotransformations in Drug Metabolism / ROBERTA S KING A Comprehensi......transformation in Drug Discovery......ATI, YANG YUAN In Vivo Drug Metabolite Kinetics / ZHENG Y......sed Proteomics Methods for Quantifying Drug-Metabolizing Enzymes and Transporters /...... S Smith, SUN MIN JUNG, JIAPENG ......chnologies for In vitro and In vivo Studies. ......SHARP Accelerating Metabolite Id......tions of Drug Candidates to Enhan......tions of Drug Candidates to Impro......ructural Alert and Reactive Metab......ept as Applied in Medicinal Chemistry to Minimi...
- 件名Drugs--Metabolism--Handbooks, manuals, etc Drugs--Met...
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- 内容細目Natural products in drug discovery......ern approaches in the search for......lead compounds in medicinal chemistry / Eliezer J. B......los A.M. Fraga and Lidia M. Lima ......ural compounds in drug discovery and development / ......tion of plants and their constitu......tural products in discovery of new anti-infective agents ......aximiliano Sortino ... [et al.] ......s / Luiz C. Klein-Junior, José R. Santin and Sérgio F. de Andrade Recent progress in the chemistry and biology of pac......itaxel (Taxol) and related taxane......Qi, Jielu Zhao and David G.I. Kingston Cancer ch...... / A. Douglas Kinghorn ... [et al.] Medicinal p...
- 件名...Pharmaceutical chemistry. Plants, Medicinal--metabolism. Drug Discovery. ...
- タイトル標目Wiley series in drug discovery and development.
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- 内容細目...ives Synthesis and Applications: ......ate-of-the-Art and Perspectives 1.1 Introduction 1.2 ......ide: Synthesis Methods and Chemistry Alteration 1.3......xide Reduction and Functionalizat......MGs 1.5 Concluding Remarks Ackno......ionuclides 2.1 Introduction 2.2 ......Anionic SeO42− and Cationic Sr2+ ......plications 3.1 Introduction 3.1.1 Photothermal and Photodynamic T......y 3.1.2 Bioimaging and Drug/Gene Deli.......1.5 Tissue Engineering and Regenerative Medicine 3.2 Conclusio......odetectors 4.1 Introduction 4.2 ......Mechanism Enabling Photodetectio......ciency 4.4.4 Gain 4.4.5 Response...... 4.5 Synthesis Methods for 2D Materials 4.5.1 Mechan...
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- 並列タイトル等（連結）（Methods and Principles in Medicinal Chemistry）
- 並列タイトル等（Methods and Principles in Medicinal Chemistry）
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- 内容細目...omplexions, ancinet and moderne custom......er-world, wherein are described ....... Very usefull and necessary for ......asters, pilots and seamen, as all...... for marchants and others by Piet......more exact, plain, and easie introduction into all geograph......young noblemen and gentlemen, the like not printed in English by Peregrin Clifford Chamb......ter-world, shewing al the sea-co...... library, containing, extracts and abridgments of......luable books printed in England, and in the forreign j...... sorts of learning by anon Lex m......ompanion. containing all the laws and statutes relating to merchandize. wherein our ...
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- 一般注記Description based on: Vol. 20 ([2004]) Title from cover Each issue has a distinctive title
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- 目次・記事Bioinformatics : fro...... to drugs Chemoinformatics in drug discovery......ends synthetic medicinal chemistry Bioisosteres in medicinal chemistry Lipophilicity in drug action and toxicology Ear......evelopment : Bringing a Preclinical Candidate to the Clinic Data mining in drug discovery Chirality in drug research ......ecular biology in medicinal chemistry Prodrugs and targeted deliv......ies Microwaves in organic and medicinal chemistry Molecular desc......ptors for chemoinformatics Pharmacokinetics and metabolism in drug design Ev......ary algorithms in molecular desi......ted techniques in drug discovery Protein-protei...
- 関連情報Bioinformatics : fro...... to drugs Chemoinformatics in drug discovery......ends synthetic medicinal chemistry Bioisosteres in medicinal chemistry Lipophilicity in drug action and toxicology Ear......evelopment : Bringing a Preclinical Candidate to the Clinic Data mining in drug discovery Chirality in drug research ......ecular biology in medicinal chemistry Prodrugs and targeted deliv......ies Microwaves in organic and medicinal chemistry Molecular desc......ptors for chemoinformatics Pharmacokinetics and metabolism in drug design Ev......ary algorithms in molecular desi......ted techniques in drug discovery Protein-protei...
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