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- 並列タイトル等（連結）老化過程におけるカロリー制限によるGlutathioneとThioredoxin systemの調節
- 並列タイトル等老化過程におけるカロリー制限によるGlutathioneとThioredoxin systemの調節
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- 内容細目pt. A. Monothiols and dithiols, protein thiols, and thiyl radicals pt. B. Glutathione and thioredoxin : thiols in si......l transduction and gene regulation.
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- 要約等...ough genes for glutathione and thioredoxin antioxidant sy......er blockade of glutathione and thioredoxin is useful in e...... inhibition of glutathione and thioredoxin systems. Highe......ession of five glutathione S‐transferase ......>, A2, M4, O2, and P1</jats:itali......:italic>mol/L) and auranofin (0.2......sed to inhibit glutathione S‐transferase ......</jats:italic> and thioredoxin reductase, res......ncer spheroids and fibroblasts: <......ncer spheroids and fibroblasts: <......:5, 1:5, 1:10, and 1:20. Cancer‐s......e presentation and delayed tumor ......ently survived and accumulated ph...... inhibition of glutathione S‐transferase <jats:italic>π<...
- 件名Cancer Research Radiology, Nuclear Medicine and imaging Oncology
- 参照...Drug Screening and Personalized T......ene expression and induce vascula...... Heterogeneity and Flexibility of Cancer Stem Ce...
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- 参照...hemoresistance and Invasiveness o......cer stem cells and regulation by ......mal niche Iron and thiol redox si......tic, metabolic and immunological ......tasis (Review) Glutathione Primes T Cell ......lnerability of Glutathione Metabolism in ......iciency toward Glutathione Transferase Ov...... Heterogeneity and Flexibility of......ls Efficacy of glutathione inhibitors for......romotes breast and endometrial tu......ic alterations and enhanced hypox......c malignancies and the era of targeted therapy P...
- 参照Selective Modification of Glutathione Metabolism A spatially and temporally res......tumours Understanding the Warburg......nit Deficiency and Gender as Dete......en Homozygous, and Proposed Model for Moderate Glutathione Deficiency Whe......detoxification and tumorigenesis ...... arthritis: a randomised trial Re......eactive oxygen and nitrogen speci......matory disease and progression to......cer System xc− and Thioredoxin Reductase 1 Co......atively Rescue Glutathione Deficiency Akt......ive Senescence and Oxidative or O......ure Senescence and Sensitizes Cel......species levels and radioresistanc......tohepatitis in glutathione-deficient mice High cancer su...
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- 参照...nder Reductive and Oxidative Stre......cardiac injury and oxidative stress via modulati...
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- 参照...ibitor OBP‑801 and amrubicin synergistically inh...
- 出版者（掲載誌）Springer Science and Business Media LLC
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- 著者標目...ichael Knudson Andrean L. Simons
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- 要約等...reased glucose and hydroperoxide ......ors of glucose and hydroperoxide ......l Design: A549 and NCI-H292 human...... inhibitors of glutathione (GSH)- and thioredoxin (Trx)-dependen......foximine (BSO) and auranofin, res......vely] in vitro and in vivo.</jats......hanced in A549 and NCI-H292 cells, and this combinati......cells with BSO and auranofin, at ......r cell killing and sensitivity to......on of both GSH and Trx, which wer...... show in vitro and in vivo that s......ibition of GSH and Trx metabolism......er cell growth and induce chemosensitization by ...
- 参照...iciency toward Glutathione Transferase Overexpressing Ca...
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- 要約等...omplex disease and a global burde......ired mutations and metabolic repr......he high inter- and intratumor het......wth advantage, and their resistan......apy treatments and patients’ prog......lar metabolism and growth, exhibi...... both negative and positive activ......th-favoring demands, numerous con......ike 2) pathway and induction of c......se involved in thioredoxin (TRX) and glutathione (GSH) systems,......e NRF2 pathway and TRX and GSH systems, w......nical findings and their relevanc......carcinogenesis and anticancer treatments.</jats:...
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- 要約等...elenoproteins, and excess selenit......x systems: the thioredoxin (Trx) system and glutathione (GSH) system. ......tein synthesis and SeNP formation......, <i>trxB</i>, and <i>trxC</i>) and GSH (<i>gshB</i> and <i>gor</i>) sy......e sensitivity, and selenoprotein ......, <i>gshB</i>, and <i>gor</i> wer......e Δ<i>trxA</i> and Δ<i>trxB</i> s......at <i>trxA</i> and <i>trxB</i> ar......s both the Trx and GSH systems, but selenoprotei...
- 件名glutathione thioredoxin Escherichia coli selenoprotei...
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- 件名General Earth and Planetary Sciences General En...
- 参照...f the Cysteine–Glutathione Axis in the Pr......atory roles of glutathione in NLRP3-infla......ediated immune and inflammatory responses
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- 件名General Biochemistry, Genetics and Molecular Biology
- 参照...ough oxidation and reduction of p......fidated states Thioredoxin-1 maintains mitochondrial fun...
- 著者標目... S. Martin Fernando Ogata Colin G. Miller Michae...
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- 参照Iron and thiol redox si......i-Inflammatory Thioredoxin Family Protein......re, Healthcare and Aging Care A M......e Detection of Glutathione 金化合物Auranofinのがん微小環境特異的抗がん活性
- 著者標目Moran Benhar Iart Luca Shytaj Jonathan S. Stamler Andrea Savarino
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- 要約等...ion of protein-glutathione mixed disulfid......diolabeled the glutathione pool with ......idant diamide, and analyzed cellu......lectric point, and immunoblotting as thioredoxin (Trx). Incubat......human Trx with glutathione disulfide or ...... -nitrosoglutathione led to the for......sence of NADPH and Trx reductase....... intracellular glutathione/glutathione disulfide ratio, an indicator...
- 参照...steine Adducts and Their Stereoselective Formati...
- 著者標目Simona Casagrande Valentina Bonetto Maddalena ...