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- 内容細目...tors Affecting Metabolism / ROBERTA S KI......sformations in Drug Metabolism / ROBERTA S KI......nsformation in Drug Discovery / JO......G YUAN In Vivo Drug Metabolite Kin......or Quantifying Drug-Metabolizing Enzymes and Transporters /......s for In vitro and In vivo Studie......difications of Drug Candidates to Enhan....../ ALA F Nassar Drug Design Strateg......difications of Drug Candidates to Impro......ameters of New Drugs / ALA F NASSA......ructural Alert and Reactive Metab......he Toxicity of Drug Candidates / ALA F ......oxicity Arrays and Enzyme/ DNA Bi......LI G HVASTKOVS Drug Interactions. ...... Regulation in Drug Metabolism and Disposition / ...
- 件名Drugs--Metabolism--Handbooks, manuals, etc Drugs--Metabolism. Pharmaceutica...... Preparations--metabolism
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- 内容細目...kin morphology and permeation pat......icals Chemical disposition in skin Skin metabolism of chemicals T......n of chemicals and their kinetics......hes, plasters, and cataplasms Yas......ecent advances and future perspec......lles in dermal and transdermal de......tals in dermal and transdermal de...... Iontophoresis and electroporatio......hiro Shikida 著 Drug delivery to-sk......ated topic: prodrug approach Relat......lied chemical candidates Selectio......lied chemical candidates: transdermal drug delivery syste......l S. Roberts 著 Drugs in topical fo...... a transdermal drug delivery syste......ety evaluation and alternatives to animal testin...
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- 内容細目...lassification, and chemical properties of drugs Drug administration and distribution Drug elimination El......s More complex and model independ......ls Kinetics of metabolism and excretion Furt...... of clearance, and physiological modelling Drug formulation : ......bioequivalence and controlled-rel......armacogenetics and pharmacogenomi......l pharmacology and age-related ph...... of disease on drug disposition Quantitative p......concentrations and effect, and pharmacokineti....../PD) modelling Drug monitoring in therapeutics Drug interactions Drug metabolism and pharmacokinetics in toxicolog...
- 件名Pharmacokinetics. Biopharmaceutics. Drugs -- Metabolism. Pharmaceutical Preparations -- metabolism.
紙雑誌
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- 並列タイトル等（連結）Drug metabolism & disposition Recent research developments in drug metabolism and disposition
- 並列タイトル等Drug metabolism & disposition Recent research developments in drug metabolism and disposition
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- 著者標目... Janefeldt Alexandra Peric Julia ......ndorf Tommy B. Andersson
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- 参照Tissue distribution and characterizati...... P450-mediated metabolism of neonicotino......s, dogs, rats, and humans Duplication, Loss, and Evolutionary F......s in the liver and small intestin......nal expression and comparative ch......): Low phase I and phase II metabolism activities Cha......P450-dependent metabolism against acetamiprid in the mu...
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- 件名Drug Discovery Pharmaceutical Scie...
- 参照...on Efficiency, and Peptide Stability
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- 参照...er intravenous drug administration
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- 件名General Pharmacology, Toxicology and Pharmaceutics
- 参照VARIDT 1.0: variability of drug transporter database
Preclinical experimental models of drug metabolism and disposition in drug discovery and development
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- 件名General Pharmacology, Toxicology and Pharmaceutics
- 参照...reconstitution and drug metabolism capabilities
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- 内容細目...olymorphism in drug abuse / Edward......ictoria Otton, and Rachel F. Tynd......nol on cocaine metabolism and disposition in the rat / R......otine kinetics and metabolism in humans / Neal L. Benowitz and Peyton Jacob I......nhibitors of anandamide breakdown......ale G. Deutsch and Alexandros Makriyannis......lly related to drug toxicities / N......astognoli, Jr. and Kay P. Castagn......the toxication and detoxication o......f amphetamines and their metaboli......ds, inhalants, and other drugs of abuse / Ro......ter T. Thomas, and Hemendra N. Bh......n studies with drugs of abuse / Yu......etoxication of drugs of abuse / John R. Cashman A...
- 件名Drugs of abuse -- Metabolism Drugs of abuse -- M......c detoxication Drugs of abuse -- P......inetics Street Drugs -- metabolism Street Drugs -- pharmacokinetics Substanc...
- 原資料等に関する注記...ept. of Health and Human Services......l Institute on Drug Abuse, 1997 SUPTDOC番号: HE 20....
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- 要約等<jats:p> Most clinically used drugs are metaboliz......tribute to the metabolism of over 50% of......linically used drugs. In the last ......, the function and regulation of ......imately 30% of drug metabolism is carried out......in controlling drug efficacy and adverse reacti......tant aspect of drug development. </jats:p>
- 参照...se involved in drug hydrolysis and lipid metabolism
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- 参照Pharmacokinetics and bioequivalence......s under fasted and fed conditions
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- 並列タイトル等（連結）Pharmacogenetics in drug-metabolizing e......ine activation and disposition
- 並列タイトル等Pharmacogenetics in drug-metabolizing e......ine activation and disposition
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- 参照Transcriptional and Epigenetic Con......G Cells CYP1A1 and CYP1A2 express......ent between 2D and 3D culture of ......ne expressions and tolerance to h......tween 2D Cells and 3D Spheroids in Human Lung Ca...
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- 参照...xomil in Liver and Intestine The Disposition of Prasugrel, ......nit structure, and metalloenzyme ......biotics in rat and human A Phase ......nism of action and clinical devel......he Human Liver and Intestine Metabolism and disposition of [<sup>14</s......o humans, dogs and rats Observati......cally Relevant Drug Interaction in...... Valproic Acid and Carbapenem Ant...... from Marketed and Investigational Prodrugs Carboxylester......of Clopidogrel Metabolism and Activation Int......lectrophoresis and kinetics under......ring intrinsic and extrinsic cofa......ulate activity and stability of h......ing Sorivudine and 5‐fluorouracil; a clinically ...
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- 著者標目Ayşe Ufuk Norikazu Matsunaga David Hallifax Aleksandra Galetin