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- 要約等The hypoxia response regulated prim......cell survival, and angiogenesis t......, acetylation, and DNA methylatio......ulation of the response to hypoxia. Eu......ne methylation and demethylation,......en to function and are induced by......n cancer cells and that they may ......chanism by HIF and histone demethylase such as J...
- 参照... under hypoxia and enhances ancho......pendent growth and aggressiveness......onformation in Response to Hypoxia Enh......cible Factor 1 and KDM3A Therapies Targeting Epi...
- 参照...ethylimination and demethylation ......rks to promote androgen-receptor-......iption Obesity and metabolic synd......ifferentiation and disease Role o......ene expression and obesity resist......lator of HIF‐1 and is down‐regula......hylases JMJD1A and JMJD2B Are Tra...... modifications and global repress......lates Cellular Responses to Hypoxia by...... Activation by Androgen Receptor ......ycling hypoxia and free radicals ......e angiogenesis and radiotherapy response Oxygen sensing......ling in cancer and approaches to ......nt, physiology and disease The Hi......gen Receptor α and Hypoxia, and Is a Key Mediator of Estrogen...
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- 要約等...nical systems, and materials scie...... (3D)-tissues, and microphysiolog......ure, function, and responses with physiolo......ressed in drug discovery and development. T......netics, safety and efficacy of ne......haracteristics and long-term main......models in drug discovery and development ca......een developers and users. Such ef......delivering new and improved medicines to patient...
- 件名...)-culture drug discovery and development translational res...
- 参照...d Hyperplastic and Proinflammator......rrier function and antibody trans......of Organ-Level Response to Clinical Dr......get-Based Drug Discovery for First-in-C......e-free culture and real-time barr......harmacokinetic and pharmacologica......ive Physiology and ADME/Tox Funct...... Liver Biology and the Tissue Response to Injury in B......c Advancements and Clinical Appli......ology for drug discovery Technical aspe......ory Chemokines and Neutrophils Translational Ass...
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- 要約等...est techniques and strategies use......rary synthesis and screening, mac......racterization, and unique applica......methodologies, and Part Two descr......cles libraries and their subseque......sses the study and characterizati...... interactions, and Part Four intr......sary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known....... Cutting-edge and comprehensive,......ycles: Methods and Protocols is a......or both novice and expert researchers looking to...
- 内容細目... of Structured and Functional Pep......inker Scalable and Efficient in p......rocyclization, and Simultaneous F......c Peptides The Discovery of Peptide Mac......ein Misfolding and Aggregation by......PPS Technology and Ultra-Throughp......cle Peptide Ligands by Means of t......yclic Peptides Discovery of Antimicrobi......osomal Escape, and Cytosolic Entr......lic Peptide Ligands to Target Proteins and Chemical Epito......es using ELISA and Fluorescence P......rating Peptide and to Tether Bioa......es Development and Characterizati......es Cyclization and Self-Assembly of Cyclic Pepti...
- 著者標目Coppock, Matthew B. Winton, Alexander J.
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- 要約等...steps involved and will serve as an ideal refere...
- 内容細目...ccines: Design and Development Co......nt of Vaccines and Adjuvants 2.2......., Dose Volume, and Administration.......5 Dose Number and Dosing Interva......4 Genotoxicity and Carcinogenicit......es of Vaccines and Populations fo......es an Antibody Response Mean? 3.3.4 CellularMethods f...
- タイトル標目RSC Drug development and pharmaceutical science
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- 内容細目Chromatin Structure and Function in Ne......igin, function and transmission o......folded protein response in fungi From ......stems Genetics and genomics decip......ary metabolism and development Fu......on of proteins and secondary meta......s towards drug discovery in fungi Explo......of fatty acids and their derivati......odeterioration and Bioconversion ......New workhorses and new uses using marine fungal ...
- 関連情報...tems for basic and applied research
- 掲載誌...tems for basic and applied research
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- 要約等...ul in the past and have drastical...... the incidence and lethality of m......ne development and vaccines targe......l as adjuvants and animal models ......sible vaccine candidates are outlined and discussed in d......, microbiology and medicine."--Publisher's websi...
- 内容細目... Ian J. Amanna and Mark K. Slifka......as G. Pauthner and Lars Hangartne......Immunogenicity and immunodominance in antibody responses / Monique Vogel and Martin F. Bach......colm S. Duthie and Steven G. Reed......fanie A. Krumm and Katie J. Doore......ls for vaccine discovery and design / Deepika Bhullar and David Nemazee
- 関連情報Current topics in microbiology and immunology
Solanum tuberosum : methods and protocols (Methods in molecular biology ; 2354) (Springer protocols)
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- 要約等...cs approaches, and bioinformatics, and finally, the a......sary materials and reagents, incl......roubleshooting and known pitfalls, and step-by-step, ...... Authoritative and practical, Sol......rosum: Methods and Protocols aims to provide a c...
- 内容細目...tato as a Crop and Practical Appr......tato Molecular Response Yeast-2-hybrid......ns in Research And Translational ...... Biotic Stress Responses In Potato (So......hodologies for Discovery and Quantitative P......omputer Vision and Less Complex I......regant RNA-Seq and high-Throughpu...... potato tubers and plants
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- 要約等Systems Immunology and Infection Micr......dels, diagrams and flowcharts to ......ent procedures and help users understand the results of......ems immunology and infection micr......c inflammation and immune responses in restoration and regeneration p......ystems' innate and adaptive immun......ematic genetic and epigenetic pat......is introduced, and the systematic genetic and epigenetic pat......ig data-driven and systems-driven......ems immunology and infection micr......ystems biology and bioinformatics......identification and systems drug d......tic immunology and infection in a......readers understand the related biological networ...
- 内容細目...atabase mining and systems b... I......Systems Innate and Adaptive Immun......n of defensive and offensive mole...... in the innate and adaptive host-......aling pathways and their cellular......ions in innate and adaptive immune responses during infect......ematic Genetic and Epigenetic Pat......ls 15. Genetic-and-epigenetic hos......an macrophages and dendritic cell......ucting genetic-and-epigenetic int......nt strains of Candida albicans in......ematic Genetic and Epigenetic Pat......sive Mechanism and Systems Drug D......thogen genetic-and-epigenetic net......m via for drug discovery: A sys... 20. Systems multipl...
- 件名...models Allergy and Immunology--Mathematical mode...
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- 要約等...omic take-off, and managing worke......assed the US standard of living a...... rising wealth and educational at...... growth theory and highlights the......ial influences and political inst......e-income trap, and for researcher......es for current and future Singaporeans"--
- 内容細目...regate Economy and Its Heterogene......atter Living Standards Jobs Infla......ast Challenges and Policy Responses Going Forward 3.Standard of Living C...... Capital Small and Large Firms 4.Jobs and Business Fluct......loyment Shocks and Propagation Me...... 5.Wage Growth and Wage Inequalit...... Flow of Goods and Services Flow ......tunism Capital and Labour Entrepreneurs and Financiers Firm-specific and General Traini......ocial Cohesion and Political Equi...... Fundamentals, and Choices New Ch......e Good Economy and the Good Life ...... Collaboration and Social Surplus Hope Discovery Human Relationships Economic ...
- タイトル標目Advanced research on Asian economy and economics of other continents...
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- 内容細目...s : challenges and solutions / Ga......zekely-Klepser and Scott Fountain......g in biomarker discovery / Michael E. B......oaches in drug discovery and development / ......rey D. Thomas, and Diane Alessi A......tical research and development / Qiuwei Xu and William H. Sch......lar biomarkers and imaging studie......lrike Fiedler, and Joachim Drevs ......les of success and failure in pre...... Sara Tombelli and Marco Mascini ......awrence Lesko, and Janet Woodcock......l of in silico and in vitro appro......g interactions and ADMET/TOX prop......nneth Bachmann and Sean Ekins In ......ations in drug discovery and development : concepts an...
- 件名...ological. Drug Discovery. Drug Evaluation, Preclinical...
- 著者標目Williams, J. Andrew.
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- 内容細目The beginnings The discovery of fission and Einstein's letter Marshall and the geneses of......nty, the bomb, and the Interim Co......onal surrender and a planned invasion Potsdam and Trinity Japan's response to the Potsdam......ion, Hiroshima and Nagasaki Japan surrenders A n...
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- 要約等...ists to understand ZIKV and how to mitigat......nt, treatment, and prevention of ...... purification, and ways to titrat......ar techniques; and a discussion o...... better understand this pathogen.......sary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known....... Cutting-edge and practical, Zik......Virus: Methods and Protocols is a......or both novice and expert scientists interested ...
- 内容細目Zika Virus: A Brief History and Review of its ...... Purification, and Titration Eval......et Digital PCR and Immunohistoche......osorbent Assay and Quantitative R......ion Production and Purification o......ation using Strand Displacement I......thermal Method and Sequencing usi......P) Development and Validation of ......qPCR, RT-LAMP, and RT-RPA A Porci......terferon Alpha Response Isolation and Detection of Z......mph Node Cells and Splenocytes Discovery of Zika Virus Dependency and Restriction Fa......ltiple Tissues and Cell Types Dur......tal Astrocytes and Tissue Explants as Ex Vivo Mo...
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- 要約等...body sequences and structures, mo......ody structures and dynamics, prediction and optimization of biological and biophysical pr...... interactions, and computer-aided......ity maturation and beyond. Writte......sary materials and reagents, incl......roubleshooting and known pitfalls, and step-by-step, ...... Authoritative and cutting-edge, ......to be a useful and practical guid......ew researchers and experts looking to expand their knowledge
- 内容細目Antibody sequence and structure anal......ng of Antibody and T Cell recepto...... for humanized and fully human th......ions Assessing and engineering an......g experimental and computational ......ope Prediction and Design for Ant......dy Development and Detection Info......daptive immune responses to infection ......iotherapeutic Candidates Structur......s for Antibody Discovery Analyzing anti......ion sequencing and machine learning A computatio...
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- 内容細目Virtual screening for lead discovery / Yat T. Tang and Garland R. Marshall Co......ter-aided drug discovery and development / ......e site mapping and receptor-based......ude to docking and de novo/fragment-based ligand design / Ashut......h Tripathi, J. Andrew Surface, and Glen E. Kellog...... of structural and biological pro......Jennifer Aral, and Les P. Miranda Fluorescent and lanthanide labeling for ligand screens, assays, and imaging / Jati......ay for protein and small molecule...... of peptide ligands for human pla......Vaidhyanathan, and GIovanni M. Pa......ellular growth and viability / Pa......Delira Robbins and Yunfeng Zhao Evaluation of an...
- 件名Drug Design. Drug Discovery. Drugs--Design. Pharmacology....
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- 要約等...ID-19 outbreak and provides an in......sed algorithms and models for dat......ID-19 symptoms and its possible r......lligence tools and technologies to track and forecast COVID......cates insights and viewpoints fro......regarding risk and resilience ana...... policy making and operations of ......chine learning and data science a......hted to gather and aggregate data......ed to COVID-19 and to diagnose th......earch outcomes and inspiring new ...... control such pandemic
- 内容細目...ntents Editors and Contributors 1......f Data Science and Its Associated......s in COVID-19 Handling 1 Introduc......entify, Track, and Forecast Coron...... Use of Robots and Drones to Ster......Food Delivery, and Perform Emerge......n Order 5 Drug Discovery and Pattern Matchi......s in Screening and Tracking of Co......Opinion Mining and Sentimental An...... Science Norms and Guidelines 15 ......gration of IOT and Cloud Computin......D-19 Detection and Diagnosis 17.1......gence (AI) in Handling Pandemic 4 Artifici......D-19 Detection and Monitoring 3.1......mell (Anosmia) and Loss of Taste (Ageusia) Tests...
- 件名COVID-19 Pandemic, 2020---Da......hine learning Pandémie de COVID-19, 2020---Info...
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- 内容細目...lassification, and amino acid seq...... Wang, Xia Li, and Michael Zaslof......lated research and the applicatio......ded prediction and design of nove......Guangshun Wang Discovery of novel antim......rial chemistry and high-throughpu......ane properties and the design of ....../ Richard M. Epand and Raquel F. Epand Non-membrane t...... / Ju Hyun Cho and Sun Chang Kim ......wards the free and active form of human LL-37 and the design of ......Paul A. Janmey and Robert Bucki R......n / John White and Ari J. Bitton ......ne tuning host responses in the face o......emerging roles and clinical appli......nna M. Easton, and Robert E. W. Hancock.
- タイトル標目Advances in molecular and cellular microbiology ; 18.
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- 要約等The pace and sophistication...... series is a stand⁰́₀alone text t......eases, global pandemics, patent l......drug products, and novel therapie...... property law, and regulatory sci......horough understanding of medicine......he patient⁰́₉s and the provider's......opics covered, and the expertise ...... undergraduate and graduate stude...... policymakers, and biomedical res......try, academia, and governments gl...... perspectives, and issues in medi......tury.Volumes 1 and 2 in this seri......al instruction and training. They......rnal medicine, and the other spec......ent, diagnose, and treat disease.......biostatistics, and big data. Clinical specialtie...
- 内容細目...G. G. Donders, and ISIDOG COVID-1......tus Maan Zrein and Eric Chatelain Present and Future of Carb......z Suay-Garc©Ưa and Mar©Ưa Teresa ...... INTELLIGENCE, AND BIG DATA Human......eld, Tad Hogg, and Robert A. Frei......igence in Drug Discovery: What Is New, and What Is Next? ......igence in Drug Discovery Rae Lawrence How Big Data and Artificial Int...... the COVID-19 Pandemic Nicola Lui......riano Martini, and Jianhong Wu Pa......emodescriptors and Biodescriptors......₉⁰́₄Challenges and Opportunities ......ert Barkovich, and Maria Palombin......, Jay D. Mason and Sally L. Hodder EDITORIALS AND PERSPECTIVES A Future Perspec...
- 件名...g data Allergy and Immunology Immunologie Microb...
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- 要約等...ily experience and imaginations o......people in town and country alike, and figured promin...... in literature and art. They also......rce of symbols and stories in their myths and folklore, and were central t......uals of augury and divination. Je...... all this rich and fascinating material for the ...
- 内容細目...n ; 5. Hunting and fowling ; 6. Cooking and eating ; 7. Fa......; 8. Captivity and domestication ; 9. Sports and entertainments...... Relationships and responsibiliti......t 4. Invention and discovery. Introduction ......3. Observation and enquiry Part 5......on ; 14. Omens and auguries ; 15. Magic and metamorphosis ; 16. Signs and symbols Part 6......18. Messengers and mediators ; 19. Mother Earth ...
- 件名...lklore Animals and civilization--Greece Animals and civilization--...... Birds Animals and civilization. Birds. Birds--M...
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- 要約等...w of the field and practical hint......ts in academia and industry. Chap...... adjuvantation and delivery, and preclinical and clinical devel......sary materials and reagents, step......ory protocols, and tips on troubleshooting and avoiding known...... Authoritative and cutting-edge, ......cines: Methods and Protocols aims...... between basic and applied scient......a, government, and industry to develop future so...
- 内容細目...gy: Generation and Testing of Stable and Immunogenic mR......ses Generation and Evaluation of ...... with Antigens and Functional Pro......Based Vaccines Discovery and Subtyping of N......pecific T-cell Responses for Cancer Immunotherapy: Ad...
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- 要約等...g fire, flood, and other disaster......chnical skills and a rigid protoc......detailed steps and procedure befo...... irreversible, and inevitable, as...... Three Mile Island in 1997, Chernobyl in 1986, and Fukushima Daii......vitable risks, and transforming t......hensive understanding on effectively managing nu...
- 内容細目...r Power Plants and Their Potentia......lopment; 1.1.1 Discovery of Fission; 1.......r Power Plants and Their Potentia...... Three Mile Island (TMI) Accident......nvisible Risks and Unknown Conseq......r Plant Siting and Environmental ......vity; 2.3 Data and Research Metho......ities in Urban and Non-urban Area......s in 1990-2000 and 2000-2010; 2.8......er Emergencies and Their Manageme......; 3.1 Disaster and Emergency Mana......ower Emergency and Response; 3.4 Projection of Plume Path...