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- 要約等...ty, especially in the developed countries including Japan. Estrog......ate are potent inhibitors of bon......nd they have clinical relevance ......otic fractures in postmenopausal......ompliance of aminobisphosphonate...... regimen is moving to a weekly o......n. Both cathepsin K inhibitors and mo......on, we need to increase bone for......, particularly in elderly patien......bone turnover. In the U.S., Euro......lready started intermittent para......hyroid hormone injection and/or oral strontium ...
- 参照...thod for measuring osteoclast fo...... impedance Platinum nanoparticle......through scavenging of reactive o......ecies produced in RAW264.7 cells......but-2-enonyl)aminobenzo〔b〕furan: a novel select...
- 参照...onate for treating and preventing postmenopausa......is RANK ligand inhibition with d......ronate Therapy in Postmenopausal......vel Cation-Sensing Mechanism in Osteoblasts Is......Risk Reduction in Postmenopausal......a Randomized Clinical Trial COMM...... Are the Endocrine Society's Clinical Practice Guidelines on Androgen Therapy in Women Misguide......en Plus Progestin on Risk of Fra......ture and Bone Mineral Density<SU......Women's Health Initiative Random......SUBTITLE> Vitamin K and the Prev......ures and Bone Mineral Density in Postmenopausal......ency: An Endocrine Society Clinical Practice Guideline Effects of Raloxifene on Car...
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- 並列タイトル等（連結）Recent advances in clinical pharmacology
- 並列タイトル等Recent advances in clinical pharmacology
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- 改題等に関する注記Continues: Advances in pharmacology and chemotherapy
- その他のタイトルAdvances in pharmacology and chemotherapy
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- 要約等Medicinal plants and t......d products remain as an indispensable sou......d therapeutics including wide availabi......reports from clinical studies testifying to the effica......safety of medicinal plants and phytochemicals in ameliorating several human......hanisms underlying the health be......of herbal medicines. Nevertheles......n of bioactive ingredients, stan......ducts and drug interactions remain to be further studied. In this book, we ......rs on the medicinal properties a......action of medicinal plants, plant species and p...
- 内容細目The effect of curcumin supplementatio...... wave velocity in patients with ......ized, double-blind, placebo-cont...... Role of curcumin in regulating long noncoding RNA expression in cancer / Abolfazl Amini [and 7 others......ffect of curcumin phytosome on t......se: a double-blind, randomized, ......fects of curcumin phytosomes against high-fat diet-induced atheroscl......[and 8 others] Intravenous curcumin mitigates athe......is progression in cholesterol-fe...... role of curcumin in gastrointestinal cancers / Me...... others] Curcumin can bind and interact with CRP: an in silico study /......ities of curcuminoids and difluorinated curcumi...
- 件名...y Plants, Medicinal Phytochemicals Phytotherapy...
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- 要約等Histamine H<sub>3</sub>......lease of histamine and other neu......s such as norepinephrine, dopamine, and acetylcholine in the central ne......ction of histaminergic neurons f......ly distributed in the CNS and ar......logical roles, including regulation of feeding, arousal, cognition, pain, and endocrine systems. To f...... roles of H3Rs in vivo, we produ......ated with hyperinsulinemia and leptinemia, the funda......3R antagonists/inverse agonists ......o regulate feeding and body weight gain in laboratory ani...... that H3Rs are involved in the regulation of feeding behavior and ......t. Several H3R inverse agonists targeting cogni...
- 件名obesity central nervous system disorder inverse agonist
- 参照Diamine Derivatives Containing Imidazolidinylidene Propanedinitrile as a New......Class of Histamine H3 Receptor A......同定と今後の展望 Histamine H3 Receptor A......onists Go to Clinics The Influence of Mast......6 Cervical Carcinoma Cells
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- 並列タイトル等（連結）Therapeutic strategies in metastatic and......relapsed gastrointestinal stromal tumors : advances in pharmacological interventions
- 並列タイトル等Therapeutic strategies in metastatic and......relapsed gastrointestinal stromal tumors : advances in pharmacological interventions
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- 要約等...histication of advances in medicine in the past two d......ssitated a growing need for a co......current issues in medicine. Each volume in the Current Issues in Medicine series is a s......l accomplished in a user-friendly yet interconnected fo......lights current advances but also explo......slational medicine, regulatory s......ta, artificial intelligence, novel imaging tools, combination drug prod......es. While bridging the gap betwe......research, medicine, engineering, FDA law, intellectual prop......ough understanding of medicine's potential t......s perspectives in a healthcare setting. The range of topics covered...
- 内容細目... Modifications Influence Protein Aggregation in Neurodegenerat......air Management in Cancers Jehad ......oolley, Ala-Eddin Al Moustafa, a......ad Malki Advancing Clinical Cohort Sel...... M. Smith, Melvin Lathara, Holli......Brian Hill, Nalini Ganapati, Ganapati Srinivasa, Christop...... Formulation Principle to Improv......Olga Pelikh, Rainer H. Mller, an......rds Biomimicry in Theranostics M......onathan O. Martinez, IDand Ennio......PHYSIOLOGY AND PHARMACOLOGY Quantitative E......ures Selection in the Classifica......sponse Control in the Children a......lular Vesicles Involved in Intercellular Com......lcieri Circulating Tumor Cells and Personalized...
- 件名Clinical biochemistry Biochimie clinique SCIENCE--Life Sciences--General. Clinical biochemistry.
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- 件名抗VEGF薬 副腎皮質ステロイド剤 angiopoietin Tie2
- 並列タイトル等（連結）Advances in pharmacologic management (bas...
- 並列タイトル等Advances in pharmacologic management (bas...
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- 要約等This book contains a compendium of induced pluripote......reviews concerning state of the ......how they are being applied to hu......eurons develop in individuals with ......sorders, providing an unparallel......opportunity to investigate their etiology. In turn, research......and the underlying molecular and......rovide an emerging tool for futu......e are common clinical as well as cellular and m...
- 内容細目Intro Contents Ab......e Editors Modeling Neurodevelopmental Deficits in Tuberous Scler......ll Development in TSC 2.1 TSC2 Deficiency in hESCs and hiPS......way Activation in Human Neural S......4 Abnormal Purkinje Cell Differe......liosis and Myelination in TSC 3.1 Astroc......ocytes and Myelination Deficits in TSC 4 Cellular...... and Viability in TSC 4.1 Mitoch......al Dysfunction in TSC 4.2 Autophagy in TSC 5 Autism and Epilepsy in TSC 5.1 MTOR-Pathway in Autism and Epi......ic Development in TSC2-Deficient......gical Deficits in TSC 6.2 Drug Screening Assays in TSC2-Deficient......ons References Advances in Human Stem Cells and Genom...
- 件名...--Diagnosis Brain--Diseases Neur......-Diagnosis. Brain--Diseases.
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- 内容細目... biosurfactant in medicine/biomedical/pharmaceutical industries / Hami...... S. Amani and Mina Naderi Applic......as an adjuvant in medicine / Ritika Josh......biosurfactants in dentristry / R......Rana and Christine Jeyaseeland E......very systems using microbially s......a P.M. Tavares Inhibition of fibrin clot formation......d life-threatening diseases / Su......Adetunji, Abel Inobeme, Olugbemi...... biosurfactant in the destructio......ny Anani, Abel Inobeme, Awotunde......Olaniyan, Abel Inobeme, Julius K......biosurfactants in the advancement of veterinary medicine / Sib Sankar ......ions of surfactin and other biosurfactants in a...
- 件名Biosurfactants Biomedical engineering Sustainable engineering Génie biomédical Ingénierie durab...... biomedical engineering
- 著者標目Inamuddin, 1980- Adetunji, Charles Oluw...
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- 要約等...atory diseases including infections. It di......ecular factors involved in the pathogenie......ally, it underlines the growing relevance of medicinal plant-based ......stems for treating lung diseases providing maximal thera......spects of medicinal plants employed in targeting respiratory d......e of audiences including physiochemist......lational and clinical researchers working in the field of respiratory dise...
- 内容細目...ses Chapter 2. Introduction to C......seases: A Pressing Need for Nove......ter 3. Role of Indian Herbal Medicine in the treatment ......pter 4. Asthma-induced inflammatory resp......hapter 5. Medicinal plants in targeting asthma Chapter 6. Incipient need of medicinal plants in targeting chronic obstr......hapter 8. Medicinal plants in the treatment ......hapter 9. Medicinal Plants in the Treatment ......pter 11. Exploring the potential of medicinal plants in Lung Cancer Ch......Effect of Medicinal Plants against Lung Cancer ......apter 13. Medicinal Plants used in the treatment ......apter 14. Medicinal Plants used in the treatmen...
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- 要約等This book highlights recent advances in our understanding of sarcopenia and frailty in CKD. The preva......ia and frailty increases substan......ated uremic toxin in the developmen...... of muscle wasting. Further, sar......es, especially in elderly CKD pa......eper understanding of the preven......ia and frailty in CKD patients t......re basic and clinical research.
- 内容細目...ia and frailty in CKD 2 Molecula...... of muscle wasting in CKD 3 Protein Energy Wasting in Chronic Kidney......of exercise training in CKD patients 5 "Frailty in patients with ......d successful aging of the elderl......ents transitioning to dialysis in Japan" 6 Exercise interventions in dialysis patients 7 Exercise intervention for ......ogress and remaining issues 8 Role......rehabilitation in the prevention...... 9 Nutritional interventions in elderly pre-di......10 Nutritional interventions in dialysis patie......harmacological intervention for sarcopenia in CKD 12 Oral He......ive impairment in CKD 14 Polypharmacy and frail...
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- 要約等...microorganisms in various aspect......anisms are examined in depth, e.g. ap......d microbiology in agriculture, microbes in the environmen......, and microbes in human health. In turn, the book shares insights into the diverse ...... and exploited in the developmen......microorganisms in the diagnosis ......health. Presenting the latest information and findings on the applications of micr...
- 内容細目Chapter 1. Recent Trends in Plant and Micr......icide for Sustainable Crop Produ......s assets fostering sustainable agricultur......cts Chapter 4. Industrial Methan......d Advancements in Biosensor Rese......er 6. Bacteriocin: A Potential Biopreservative in Foods Chapter ...... waste for Pectinase production for its industrial applic......lecule Transmuting the Biotechno......f Metagenomics in Plant Disease ......s of Plants against Diseases Cha......Iron chlorosis in peach: Current......le of microbes in plastic degrad...... for Potential Industrial Psychr......nal Regulators in Bacillus Anthr......apter 18. Medicinal fungi: A natural source of ...
- 一般注記Includes index
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- 要約等Histamine H<sub>1</sub>......or (H1R) signaling is regulated by changing its expressio......mechanisms are involved in this regulatio......mutant H1R lacking five putative......y several protein kinases. The other......pression. Protein kinase C (PKC) signaling was suggested to be involved in this up-regula......>3</sub> muscarinic receptors (M3R) induced both down......PKC activation induced H1R phosp......expression was induced by the st......uggested to be involved in this up-regula......rgic receptors induced H1R down-......synthesis that includes the supp......tor mRNA. Protein kinase A was suggested to be involved in enhanced degradation...
- 件名down-regulation up-regulation β2-adrenergicreceptor muscarinic receptor
- 参照Stimulation of histamine H1 receptor u......egulates histamine receptor itself through acti...
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- 要約等Histamine is inactivated by the histamine-metabolizing enzyme histamine <i>N</i>-meth......sferase (HNMT) in bronchus, kidn......o be localized in the cytoplasm, but histamine is unable to ......sily enter the intracellular spa......ion as a histamine transporter as well. To investigate the involvement of OC......ted with C-terminal hemagglutinin (HA)-tagged HN......A and/or C-terminal myc-tagged r......ion. After 60-min incubation of the......cells with PBS including HA (100 μM), ......p>-methylhistamine (MHA) concent......ants was determined by the HPLC-...... alone, suggesting that OCT-2 co......ion as a histamine transporter as well and that...
- 件名histamine N-methyltransferase organic ...
- 参照...es Ischemic Brain Damage through Modulating Histamine and Regulator......f plasma histamine levels by the......y stress Histamine Clearance Thr......c Transporters in the Brain Brain Histamine <i>N</i>-Meth......or Methamphetamine Overdose Are Histamine H3 Antagonists the Definitive Treatment......te Methamphetamine Intoxication? Epigallocatechin gallate stimulated histamine production an......egulated histamine H1 receptor in oral cancer cell lines expressing histidine decarboxylase...... Role of Histamine in the Pathophysi......thma and the Clinical Efficacy of Antihistamines in Asthma Therapy Functional Ana...
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- 要約等...ters describes in detail the phy......erapy research in patients with ......ty of daily living, quality of l...... survival rate in cancer patient......vides not only information on re......programs by giving step-by-step ......ng with presenting an introduction to p......cance and new findings, the authors......y and Research in Patients with ......get up-to-date information. By sharing the latest re......er development in this field of study
- 内容細目...th related QOL in cancer survivo......uality of life in patients with gastrointestinal cancer 4 Phy......th related QOL in surgically tre......uality of life in patients with ......uality of life in patients after...... survival rate in cancer patient......sical function in patients undergoing allogeneic he......mmune function in patients with ...... for counteracting cancer cachexia-related declines in muscle mass an......ngth and the clinical assessment......cle Adaptation in Cancer Cachexi......sical activity in patients with ......sical Activity in Patients with ......ltiple frailty in elderly patien...... complications in patients with esophageal canc...
- 著者標目Morishita, Shinichiro [森下慎一郎] 井上, 順一朗 中野, 次郎,...
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- 要約等G-protein-coupled recept......superfamily of integral membrane proteins to which histamine receptors belong. Increasing numbers of proteins have been identified to interact with the C-termini of GPCRs. These interactions are implicated in targeting, trafficking, and fine-tuning of signaling of GPCRs. Alt......ough the C-terminus of the histamine H<sub>2</sub>......gested to play in agonist-induced internalization o......s of the C-termini of the other three histamine receptors are......ere is no protein identified to interact with the C-termini of histamine receptors.<br>
- 件名G-protein-coupled receptor histamine receptor C-terminus internalization
- 参照Tctex-1 augments G protein-coupled recept......iated Gs signaling by activating adenylyl cycl......Receptor signaling: new insight into its regulato......echanisms Blocking Histamine H1 Improves Learning and Mnemonic Dysfunction in Mice With Soci......ed Methamphetamine Injection
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- 要約等Accumulating evidence has ......tance of histamine in immune respons......b> receptor is involved not only in allergic inflammatory reactions but also in augmentation o......d participates in immune tolerance through interleukin-10 and transforming growth factor......ceptor, which binds to histamine with high affinity and of whic......tance of histamine in immune responses. However, since a majority o......xogenous histamine, it remains largely unkno......produced histamine is involved in regulation of such kinds of immune responses. Insight into precise roles of histamine in the immune sys......can not be obtained without correct understandi...
- 件名mast cell IgE histamine decarboxylase
- 参照...N-γ Production in Murine Splenocytes by Histamine Receptor Anta......itoneal thickening by histamine in a mouse model ......eritoneal scraping Impact of Systemic Histamine Deficiency on......mmary Adenocarcinoma and T Cells
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- 要約等Covering everything from historical and international per...... and current clinical practice, ......h Edition, remains the preeminent reference in the field. Dr....... experts who bring you the most up-to-date information avail......entific, and clinical issues you......r you're preparing for the boards, studying for recertifi......ation, or managing a challenging patient care situation in your practice. Contains fully revised......nt throughout, including numerous new videos online. Includes four new chapters: Clinical Care in Extreme Enviro......mplications; Clinical Research; and Interpreting the Medical Literature. Addr...
- 内容細目... anesthetics ; Inhaled anestheti......very systems ; Intravenous anest...... ; Nonopioid pain medications ; Intravenous drug ......very systems ; Pharmacology of neuromuscular blocking drugs ; Rever......atient positioning for anesthesi......ascular monitoring ; Perioperati......rologic monitoring ; Monitoring depth of anesthesia (monitoring brain state) ; Respiratory monitoring ; Renal patho......nd nephrotoxic injury ; Neuromuscular monitoring ; Airway management in the adult ; Spinal, epidural, a......with chronic pain ; Palliative medicine ; Anesthesia ......rgery and neurointerventions ; A......al and genitourinary systems ; Anesthesia for o...